National Institute on Drug Abuse, NIH, Contracts Management Branch, OPRM, 5600 Fishers Lane, Parklawn Building, Room 10-49, Rockville, MD 20857

A -- ASSESSMENT OF POTENTIAL COCAINE TREATMENT MEDICATIONS IN RODENTS SOL N01DA-7-8076 DUE 050597 POC Kenneth E. Goodling, Contracting Officer, Phone: (301) 443-6677, FAX: (301) 443-7595, Email: kg25d@nih.gov The National Institute on Drug Abuse (NIDA) is soliciting proposals from qualified organizations having in-house capability to screen compounds in the mouse locomotor activity and rat drug discrimination paradigms for assessment as potential pharmacotherapies for cocaine dependence. Proprietary compounds will be evaluated in established protocols, and the resulting data will be utilized by the Cocaine Treatment Discovery Program of the NIDA Medications Development Division. Offerors must indicate pos session of current DEA registration for Schedule II-V substances prior to award and apply for Schedule I registration at the time of award. It is anticipated that one (1) cost reimbursement, completion type contract will be awarded for a period of four years, with a possibility of one option year and options for additional follow-up studies. RFP No. N01DA-7-8076 will be available electronically on or about March 19, 1997, and may be accessed through the NIH Gopher and/or the Internet by using the followingelectronic mail addresses and instruction: 1) NIH Home Page (via the World Wide Web): Access the NIH Home Page by using http://www.nih.gov . Once you are at the NIH Home Page, select "Grants and Contracts"; select "NIH Gopher directory: listed under the "Contracts Page" section. Once at the NIH R&D Gopher, select "RFPs Available"; select "NIDA"; and select "RFP N01DA-7-8076". (URL: gopher://gopher.nih.gov:70/11/res/rd-rfp) 2) NIH Gopher: Point your Gopher client to GOPHER.NIH.GOV Port 70 (you should now be in the NIH Gopher). Select "Grant and Research Information"; select "R&D Request for Proposals (RFP)"; select "RFPs Available"; select "NIDA"; and, select "RFP N01DA-7-8076". Please note that the RFP for this acquisition will be streamlined to include only the Work Statement, deliverable and reporting requirements, special requirements and mandatory qualifications, Technical Evaluation Criteria, and proposal preparation instructions. All information required for the submission of an offer will be cont ained in the electronic RFP package. Following proposal submission and the initial review process, offerors comprising the competitive range will be requested to provide additiona l documentation to the Contracting Officer. Response to this RFP will be due on or about May 5, 1997. Any responsible offeror may submit a proposal which will be considered by the Government. This advertisement does not commit the Government to award a contract. Point of Contact: Kenneth E. Goodling, Contracting Officer Electro nic Mail Address: kg25d@nih.gov Telephone: (301) 443-6677 Fax: (301) 443-7595 (0059)

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