National Cancer Institute, Research Contracts Branch, Cancer Etiology Contracts Section, Executive Plaza South, Rm. 620, 6120 Executive Blvd., MSC 7224, Bethesda, MD 20892-7224

A -- MINORITY ADOLESCENT HIV RESEARCH PROJECT: A MODEL FOR COMMUNITY BASED TREATMENT & PREVENTION SOL N01-SC-71037-09 DUE 052397 POC Mary E. Landi O'Leary, Contracting Officer, 301-496-8611 WEB: National Cancer Institute, http://cbdnet.access.gpo.gov. E-MAIL: Mary E. Landi O'Leary, OLEARYM@rcb.nci.nih.gov. The HIV/AIDS Malignancy Branch (HAMB), Division of Clinical Sciences(DSC), National Cancer Institute, plans to issue a contract with the Hospital for Sick Children(HSC), Washington D.C. using other than full and open competition for A Minority Adolescent HIV Research Project, Cost Sharing Contract: (Model for Community Based Treatment and Prevention) The purpose of this contract is to identify, engage, refer, and enroll adolescents in clinical research trials of the HAMB and the NCI. The determination to use other than full and open competition was made in accordance with 41 USC 253 (c) (1) and is based upon the following factors and accomplishments: NCI, HAMB has selected HSC as the only responsible source based upon (1)The presence of a comprehensive coordinated program of care for HIV-infected adolescents which encompasses community based, accredited, inpatient and outpatient facilitates in the District of Columbia with direct care coordination and links to the clinical research program of the HAMB,NCI, NIH; (2) HSC has the presence of required equipment, extensive services and supports, materials and systems necessary to support outreach and education efforts essential to engage the target population in clinical trails; (3) HSC has the presence of required computer network and linking systems with the HAMB, NCI, NIH which provide symmetry of format, for the purposes of research data transmission and evaluation. (4) It is necessary to continue with HSC's services to prevent a significant cohort of research patients from being lost to follow-up and subsequently resulting in the major loss of research data. These services and systems were established under predecessor contract NCI NO1 SC-47037. This contract is being solicited as a Cost Sharing, Level of Effort contract with one base year and two option years. During this contract period the contractor will assume incremental financial responsibility with the alternate goal of fiscal independence. Numbered Note 22 applies as follows: The proposed contract action is for supplies or services for which the Government intends to solicit and negotiate with only one source under the authority of FAR 6.302. Interested persons may identify their interest and capability to respond to the requirement or submit proposals. This notice of intent is not a request for competitive proposals. However, all proposals received within forty-five days (thirty days if award is issued under an existing basic ordering agreement) after date of publication of this synopsis will be considered by the Government. A determination by the Government not to compete with this proposed contract based upon responses to this notice is solely within the discretion of the Government. Information received will normally be considered solely for the purpose of determining whether to conduct a competitive procurement. Collect calls will not be accepted. (0073)

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