National Institute of Allergy & Infectious Diseases, Contract Management Branch, Solar Building, Room 3C07, 6003 Executive Boulevard., MSC 7610, Bethesda, Maryland 20892-7610

A -- THERAPEUTIC STRATEGIES FOR PAPILLOMAVIRUS INFECTIONS POC Ms. Judith Rubinstein, Contract Specialist, 301-496-2509, Mr. Carl Henn, Contracting Officer, 301-496-0993 The Virology Branch, Division of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases, has a requirement for the evaluation of clinical potential of experimental therapeutic agents for the treatment of human papillomavirus infections. The requirement includes facilitation of the entry of these agents into clinical trials. The work will include delineation of viral pathogenic processes. Both in vitro and animal model systems will be used. Adequate animal facilities will be mandatory for contract award. It is anticipated that two cost -- reimbursement term contracts will be awarded, both for a period of five years. Both contracts will involve coordination of in vitro and animal model studies. RFP NIAID-DMID-98-10 will be available electronically on or about May 5, 1997, and may be accessed through the NIH Home Page of the NIH Gopher by using the following electronic mail addresses and instructions: NIH Home Page (via the World Wide Web): Access the NIH Home Page by using http://www.nih.gov . Once you are at the NIH Home Page, select Grants & Contracts, then under the "Contracts" page heading, select "NIH gopher directory" to access the "R&D Requests for Proposals (RFP)" in the gopher directory. Once in the gopher directory, select "RFP's Available"; "NIAID"; and finally, "RFP NIH-NIAID-DMID-98-10." This RFP is only available via the NIH Home Page. Instructions for this acquisition and for proper submission are set forth at the Web Site mentioned above. Following proposal submission and the initial review process, offerors comprising the competitive range will be requested to provide additional documentation to the Contracting Officer. Responses to this RFP will be due on or about June 30, 1997. Any responsible offeror may submit a proposal which will be considered by the Government. This advertisement does not commit the Government to award a contract. (0107)

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