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COMMERCE BUSINESS DAILY ISSUE OF JULY 10,1997 PSA#1884Director, USAMRAA, 820 Chandler St, Fort Detrick, MD 21702-5014 A -- BONE HEALTH & MILITARY MEDICAL READINESS (OSTEOPOROSIS AND
RELATED BONE DISEASES) SOL CBD970-0000-0008 POC Craig D. Lebo,
301-619-2036 (Site Code DAMD17) E-MAIL: Click here to contact the
Contracting Officer via email., craig_lebo@ftdetrck-ccmail.army.mil.
The following is a corrected text to CBD announcement, PSA#1881, CBD
issue of July 7, 1997: Bone Health & Military Medical Readiness
(Osteoporosis and Related Bone Diseases) -- The U.S. Army Medical
Research and Materiel Command is soliciting research proposals for
studies of bone physiology in populations of military age. This effort
is coordinated with research programs of the individual organizations
of the National Coalition for Osteoporosis and Related Bones Diseases,
and the National Institutes of Health, including the National Institute
of Arthritis and Musculoskeletal and Skin Diseases (NIAMS). The goal of
this program is to advance understanding of methods to improve bone
health of young men and women, enhancing military readiness by reducing
the incidence of fracture during physically intensive training and
reducing the incidence of osteoporosis later in life. Research insights
into fundamental mechanisms of bone biology and pathogenesis of bone
diseases (such as osteoporosis, Paget's disease of bone, and
osteogenesis imperfecta) contribute to these goals. We solicit
proposals on a broad range of basic science and clinical issues related
to biomechanical stress on the skeleton, including but not limited to
these areas of interest: (1) interrelationship of biomechanical forces
and bone cell biology, (2) influence of physical factors on bone
matrix synthesis in young adults and genetic markers of synthesis
applicable to normal and pathological conditions of bone, (3)
interacting effects of physical training with diet and other health
habits on peak bone mass development, (4) longitudinal studies of bone
physiology and bone remodeling in physically active populations,
including influences of specific types of intense physical training,
(5) physical and genetic mediators of stress fracture risk, and (6)
stress fracture prevention strategies including pharmacological and
hormonal interventions to augment bone mass and limit bone loss.
Proposals will be selected for funding on the basis of high quality
science. Potential application to military populations will be
considered in this award. Projects are typically 2-4 years in duration
and must be completed by 30 September 2003. Approximately $9.5M is
available for the lifespan of these projects. Full proposals must be
submitted according to general instructions contained in the Broad
Agency Announcement 95-1 (available on the internet at
http://www-usamraa.army.mil). Letters of intent containing a proposed
title, brief description of project scope (<150 words), and
investigator and institution identification, are due by 3 September
1997. Full proposals are due by 4:00 pm EST, 1 October 1997.
Investigators will be notified about funding recommendations by
February 1998. For further information, please write to: USAMRMC
(MCMR-PLC), Army Operational Medicine Research Program, Fort Detrick,
MD 21702-5012, FAX (301) 619-2416. Send letters of intent and 20 copies
of full proposals only to: Director, U.S. Army Medical Research
Acquisition Activity, ATTN: MCMR-AAA (Bone Health), 820 Chandler
Street, Fort Detrick, MD 21702-5014. (0189) Loren Data Corp. http://www.ld.com (SYN# 0001 19970710\A-0001.SOL)
A - Research and Development Index Page
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