DHHS, PHS, CDC, NIOSH, ALOSH, 1095 Willowdale Rd., Morgantown, WV 26505-2888

66 -- GENE CHIP EXPRESSION ANALYSIS SYSTEM SOL RP97-037 DUE 090297 POC Brenda Goodwin, 304/285-5882/Contracting Officer, Rex S. Wolfe, 304/285-5883 THIS IS A COMBINED SYNOPSIS/SOLICITATION FOR COMMERCIAL ITEMS PREPARED IN ACCORDANCE WITH THE FORMAT IN SUBPART 12.6, AS SUPPLEMENTED WITH ADDITIONAL INFORMATION INCLUDED IN THIS NOTICE. THIS ANNOUNCEMENT CONSTITUTES THE ONLY SOLICITATION; QUOTES ARE BEING REQUESTED AND A WRITTEN SOLICITATION WILL NOT BE ISSUED. This Solicitation, Request for Proposal No. RP97-037, is being issued unrestricted under Standard Industrial Classification (SIC) Code 3826 with a size standard of 500 employees. This solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 90-46. Offers shall be submitted for the following items or functionally equivalent products: (001) Gene Chip Expression Analysis System ( Affymetrix #900136 or equal); and (002) Gene Chip Sequence Analysis Software (Affymetrix #610002 or equal). Specifications: The following are functional features which must be met to be considered equal: (#1) Precision laser capable of focusing on 3 micron spot; (#2) The ability to read a genechip probe array with 400,000 cells; and (#3) The ability to perform function #2 in 5 minutes and display data at computer terminal. The gene scan equipment shall be a state-of- the-art multipurpose instrument. It will be applied to three types of genetic analysis: (a) determination of polymorphic DNA-sequence variants in potential occupational disease susceptibility genes; (b) determination of DNA-sequence mutations in oncogenes and tumor suppressor genes (e.g. p53); and (c) determination of modulation in gene expression by environmental and occupational toxins. "Time of Delivery" The Government desires delivery of all items within 15 weeks after receipt of contract. If an offeror is unable to meet the desired schedule, it may without prejudicing evaluation of its offer, propose a different delivery schedule provided it does not extend beyond the Government's required schedule of 20 weeks after award of contract. The Government will evaluate based on F.O.B. Destination (Morgantown, West Virginia) and the requirements at FAR 52.214.21 "Descriptive Literature" apply. Information provided must clearly demonstrate that the system offered meets the salient features stated or your offer may be rejected. The following FAR provisions apply to this solicitation: FAR 52.212-1, Instructions to Offerors -- Commercial Items; 52.212-4, Contract Terms and Conditions -- Commercial Items and 52.212-5 Contract Terms and Conditions Required to Implement Statutes or Executive Orders -- Commercial Items. Additionally, the following FAR clauses cited in Clause 52.212-5 are also applicable to this acquisition as follows: FAR 52.222-3 "Convict Labor (E.O. 11755)", 52.233-3 "Protest After Award (31 U.,S.C. 3553 and 40 U.S.C. 759)", 52.203-6 "Restrictions on Subcontractor Sales to the Government, With Alternate I"; 52.203-10 "Price or Fee Adjustment for Illegal or Improper Activity", 52.219-8 "Utilization of Small Business Concerns and Small Disadvantaged Concerns; 52.222.26 "Equal Opportunity"; 52.222-35 "Affirmative Action for Special Disabled and Vietnam Era Veterans"; 52.222-36 "Affirmative Action for Handicapped Workers"; 52.222-37 "Employment Reports on Special Disabled Veterans and Veterans of Vietnam Era"; 52.225-3 "Buy American Act -- Supplies"; 52.225-18 "European Community Sanctions for End Products." Offers are due September 2, 1997, 3:00 p.m. local prevailing time. Fascimile submissions are not authorized. Submit the following to DHHS, PHS, CDC, NIOSH, ALOSH, Attn: Brenda Goodwin, 1095 Willowdale Road, Morgantown, WV 26505: (1) original and two copies of a completed SF 1449, signed by an individual authorized to bind the organization; (2) Pricing Schedule for items 001 & 002 and a delivery schedule for each; (3) completed Representations and Certifications -- Commercial Items, FAR 52,212-3; (4) descriptive literature and other information for evaluation purposes; and (5) acknowledgment of solicitation amendments, if any. Offers that fail to furnish the required information, orreject the terms and conditions of the solicitation may be excluded from consideration. Information regarding this notice can be obtained from Brenda Goodwin at (304)285-5882 or by fax at (304) 285-6083. All responsible sources may submit a response, which shall be considered by the Agency. (0220)

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