National Institutes of Health, Office of Procurement Management, 6120 Executive Blvd., (EPS), Rockville, Maryland 20892-7260

66 -- MOLECULAR PROTEIN RECOGNITION SYSTEM SOL 263-97-P-(AB)-0050 DUE 091597 POC Ann Bryant,, Contract Specialist, 301/402-3080 This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued. The solicitation number is 263-97-P-(AB)-0050 and is issued as a Request for Proposal (RFP). The solicitation/contract will include all applicable provisions and clauses in effect through FAC 90-46. The standard industrial code (SIC) is 3826 and the business size is 500 employees. The National Institutes of Health, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, has a requirement to acquire one (1) each Molecular Protein Recognition System. The NIH intends to contract with Ciphergen Biosystems, Inc., 490 San Antonio Rd.., Palo Alto, CA 94306, the only known source for this equipment. The equipment shall consist of the following specifications: 1. Shall use micro-arrays to perform surface-enhanced protein affinity capture assays for detection and characterization of trace analytes by surface-enhanced laser desorption/ionization. 2. Shall use antibodies to capture capsid and recombinant proteins and identify them by mass. 3. Shall use antibodies to capture target proteins in the low femtomole range and identify them by mass and by on-chip processing, including epitope mapping. 4. Shall use only one micro liter of sample from complex fluids such as serum feces. 5. Purification shall take place on the protein chip surface. 6. Shall allow the use of metal ion (Ni) surfaces to specifically separate recombinate proteins in the low femtomole range from contaminates and allow on-chip analysis including peptide-mapping, micro-sequencing and analysis of post-translational modifications from a micro liter sample. 7. Shall use ProteinChip Arrays to perform surface enhanced neat desorption procedures for the analysis of low molecular mass analytes from 0 to 1,000 daltons. 8. Shall be designed to be operated unattended and have full analyte quantitation capabilities. The contractor shall deliver the equipment within thirty (30) calendar days after date of contract award. The Government will evaluate based on F.O.B. Destination and acceptance at (Bethesda, Maryland) and the requirements of FAR 52.214-21 "Descriptive Literature" apply. Proposals/Information provided must demonstrate the equipment's ability to meet the specifications described herein. FAR provisions 52.212-1 Instructions to Offerors-Commercial, applies to this acquisition. Award will be made to the technically acceptable low offer. A completed copy of the provision 52.212-3, Offeror Representations and Certifications-Commercial Items, is required as part of the offer. The clause 52.212-4 Contract Terms and Conditions-Commercial Items applies to this acquisition. The clause at 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders-Commercial Items applies to this acquisition. The Contractor will be paid following delivery, and acceptance of the equipment. The proposed contract action is for supplies or services for which the Government intends to solicit and negotiate with only one source under the authority of FAR 6.302. Interested persons may identify to the Contracting Officer their interest and capability to satisfy the Government's requirement with a commercial item within 15 days of this notice. A determination by the Government not to compete with this proposed contract based upon responses to the notice is solely within the discretion of the Government. Information received will normally be considered solely for the purpose of determining whether to conduct a competitive procurement. Address responses to the attention of Ms. Ann Bryant at the above address. FAX responses are acceptable at 301/402-3406. (0241)

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