National Institutes of Health, National Heart, Lung, and Blood Institute, Contracts Operations Branch, 6701 Rockledge Drive, Room 6100, MSC 7902, Bethesda, MD 20892

A -- CENTRAL LIPID LABORATORY FOR NATIONAL HEALTH AND NUTRITION SURVEY (NHANES IV) SOL NHLBI-HV-97-09 DUE 112497 POC Douglas W. Frye, Contracting Officer (301) 435-0340/Fax (301) 480-3338 WEB: ERROR --, none. E-MAIL: Douglas W. Frye, Contracting Officer, fryed@gwgate.nhlbi.nih.gov. The National Heart, Lung, and Blood Institute (NHLBI) in cooperation with the National Center for Health Statistics (NCHS) is soliciting proposals for the establishment of a Central Lipid Laboratory in support of the NCHS National Health and Nutrition Survey (NHANES IV). The NHANES IV will involve the study of a sample population of 40,000 adults and children. The Central Lipid Laboratory will: (1) be required to be CDC standardized for lipid measurements, (2) accurately measure total cholesterol and HDL cholesterol for the entire NHANES IV sample population, (3) accurately measure triglycerides for the fasting NHANES IV population, and (4) deliver the results to NCHS. The results will be used by NCHS in its NHANES IV program to monitor current lipid levels in the United States and to determine national trends in cholesterol and other lipid values by comparing the values collected in the NHANES IV with corresponding data gathered in previous surveys. The work of the Central Lipid Laboratory will be conducted in three phases. In Phase I (5 months), the Central Lipid Laboratory will measure lipid levels in about 250 samples collected over 1-2 months and prepare a Central Lipid Laboratory manual of operations for the study. In Phase II (6 years) the Central Lipid Laboratory will measure total cholesterol and HDL cholesterol in 22,200 samples with triglyceride measurement in half (11,100)of the samples. In Phase III (7 months) the Central Lipid Laboratory will assay any remaining samples or repeat measurements as required. In addition, the Central Lipid Laboratory will work with NHLBI and NCHS in preparation of journal articles to disseminate the lipid results as well as the national trends. This is not an RFP. RFP NHLBI-HV-97-09 will be available on or about October 1, 1997, with proposals due on or about November 24, 1997. SICC is 8071. Award of a contract for this study will be made only to offerors located in the United States of America. The RFP will be available on the NIH Gopher. Access is via the NIH Website (http://www.nih.gov). At the NIH Home Page select "Grants & Contracts" then select "NIH Gopher Directory" (within the contracts page). Offerors that have access to the NIH Gopher Server can access the RFP by pointing your gopher client to Gopher://gopher.nih.gov:70/11/res/rd-rfp. All information required to submit an offer is in the electronic RFP package. A hardcopy version of the RFP will be mailed to any organization unable to access the RFP online. All requests must cite "RFP NHLBI-HV-97-09" and must be submitted in writing or fax to the following address: Douglas W. Frye, Contracting Officer HLVD Contracts Section National Heart, Lung, and Blood Institute 6701 Rockledge Drive, MSC 7902 Bethesda, MD 20892 Telephone: (301) 435-0340 FAX: (301) 480-3338 (0255)

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