National Institute of Child Health and Human Development, Contracts Management Branch, 6100 Bldg., Suite 7A07, 6100- Executive Blvd MSC 7510, Bethesda, MD 20892-7510

A -- MONCLONAL ANTIBODIES SOL NICHD-IRM-98-SS01 POC Charles Newman, phone: 301-496-4611, fax 301-402-3676 WEB: NIH Home Page, http://www.nih.gov. E-MAIL: Charles Newman, Contract specialist, e-mail adress, newmanc@nih.gov. The National Institute of Child Health and Human Development (NICHD) is looking for potential contractual sources for the production of Monoclonal Antibodies in accordance with the following protocol: 1) Five BALB/c mice immunized at three-week intervals. 2) Test bleed 10 days after third injection. 3) Final boost three days before fusion. 4) Fusion of spleen from selected mouse with an appropriate myeloma cell line. 5) Cells grown. 6) ELISA testing for antibody production. 7) Cloning of antibody-producing cells. 8)Cryopreservation of clones. 9) Ascites fluid prepared in ten mice. The purpose of this synopsis is to develop a list of potential sources capable of performing the government's requirements as described. Capability Statements should be submitted within 45 days of publication of this synopsis to Mr. Charles Newman, Contract Specialist, NIH, NICHD, CMB., Executive Building, Suite 7A07, 6100 Executive Blvd., Bethesda, MD 20892 and should include details specifying how this work would be performed. Please note there is no solicitation associated with this synopsis and the government reserves the right to cancel the requirement at any time. (0280)

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