Acquisitions Management Operations Branch, NIAID, 6003 Executive Blvd, Solar Building, Room 1C38, Contracts Section, Bethesda, MD 20892-7605

A -- THAILAND IL-2 VANGUARD STUDY!! SOL N/A!! DUE 121997 POC Carolyn B. Sentz, Contracting Officer, (301) 402-2282!! The National Institute of Allergy and Infectious Diseases intends to 1) utilize an internationally recognized, collaborative research organization in Thailand to conduct and coordinate HIV clinical research, 2) develop the infrastructure and expertise to support continued clinical research, and 3) obtain proper assurance for research with human subjects. The United States Government intends to negotiate a sole source simplified acquisition with the HIV-NAT (Human Immunodefieciency Virus-Netherlands, Australia and Thailand) Research Collaborative with the primary objectives of this protocol to 1) demonstrate the safety and tolerance of IL-2 in combination antiretrovirals, 2) demonstrate immunological efficacy of IL-2 in combination with antiretrovials therapy, and 3) determine the feasibility of Thai participation as one of the sites in a future randomized controlled trial of interleukin-2. The following services and support may be acquired under this acquisition. They are: nursing services (full and/orpart-time), pharmaceutical and laboratory technician services, laboratory testing services, office administrative support, and various clinical laboratory and administrative equipment/supplies from and for use in Thailand. Because of the patient audience and location of the study, the United States Government intends to negotiate this acquisition as a sole source. Closing date for submission of written responses in forty-five (45) days after the date of this notice. See numbered note 22!! (0308)

Loren Data Corp. http://www.ld.com (SYN# 0002 19971106\A-0002.SOL)