DHHS, PSC, DAM, GAB, Room 5-101, Parklawn Building, 5600 Fishers Lane, Rockville, MD 20857

Q -- PERIODONTAL DISEASE TREATMENT PROGRAM IN NATIVE AMERICANS WITH TYPE 2 DIABETES POC Allison C. Ford, Contract Specialist (301) 443-0101, Fax: (301) 443-3849 WEB: Program Support Center, http://cbd-submit@gpo.gov. E-MAIL: Program Support Center, aford@psc.dhhs.gov. The Department of Health & Human Services, Indian Health Services, intends to solicit and negotiate on a sole source basis with the Department of Oral Biology, School of Dental Medicine, State University of New York at Buffalo, 3435 Main Street, Room 120 Foster Hall, Buffalo, New York, 14214. The purpose of this project is to develop a research protocol for and test, through a clinical trial, one or more efficacious non-surgical treatment regimens for diabetes related periodontal disease. This is a Phase II clinical trial, with the intent to improve upon the clinical findings from the previous work. The clinical trial will focus on the use of antibiotics, both locally applied and systemically, in the treatment of periodontal disease in Native Americans with Type 2 Diabetes. This investigation will assess the effectiveness of several treatment regimens and will be conducted at two USPHS, Indian Health Service dental clinics in the Pueblos of Santo Domingo and San Felipe, New Mexico. The period of performance is 36 months. A Cost-Reimbursement Contract will be awarded. See Note 22. (0316)

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