National Cancer Institute, Research Contracts Branch, Cancer Etiology Contracts Section, Executive Plaza South, Rm. 620, 6120 Executive Blvd., MSC 7224, Bethesda, MD 20892-7224

A -- COHORT AND NESTED CASE-CONTROL STUDY OF AIDS-RELATED NON-HODGKIN'S LYMPHOMA, KAPOSI'S SARCOMA AND OTHER MALIGNANCIES SOL RFP N01-CP-81017-21 DUE 022598 POC Barbara A. Shadrick, Contracting Officer, 301/435-3787 WEB: Research Contracts Branch/Current Requests for Proposal, http://rcb.nci.nih.gov/RFP/81017. E-MAIL: Barbara A. Shadrick, bs92y@nih.gov. ELECTRONIC RFP ANNOUNCEMENT. POTENTIAL OFFERORS WILL BE RESPONSIBLE FOR DOWNLOADING THEIR OWN COPY OF THE SOLICITATION AND AMENDMENTS. The Viral Epidemiology Branch (VEB), Division of Cancer Epidemiology and Genetics (DCEG), National Cancer Institute (NCI), National Institutes of Health (NIH), is seeking offerors for a new contract for an epidemiologic study of advanced HIV infection and associated malignancies. This contract will provide support for a new cohort and nested case-control study of AIDS-related non-Hodgkin's lymphoma (NHL), Kaposi's sarcoma (KS) and other malignancies. A pilot phase of this study has been recently implemented under a previous contract. This new contract will complement a number of other DCEG contracts in addition to a separate population-based study of non-AIDS NHL, but it will not overlap with any of them. The Contractor shall be responsible for the acquisition, maintenance and use of epidemiologic data bases; provision of support for collecting and handling biologic specimens; collecting epidemiologic, clinical and laboratory data; editing and collating data; creating necessary computer data records and conducting statistical analyses of these data; and responding quickly to requests involving certain priorities. This contract will NOT require the Contractor to perform laboratory assays nor be responsible for the costs of assays that are performed by various laboratories. The contractor will arrange for the collection and shipment of required specimens as well as interview, clinical and laboratory data for this cohort. The contractor shall obtain interview, medical record abstracts and blood specimens on a minimum of 5000 such subjects, which may include individuals currently under study at the NCI. It is anticipated that the proposed contract will be a cost-reimbursement, completion type contract for a five-year period of performance. All responsible sources capable of providing this support and meeting these criteria are encouraged to submit an offer and will be considered by the NCI. It is the offeror's responsibility to monitor the above Internet site for the release of this solicitation and amendments, if any. POTENTIAL OFFERORS WILL BE RESPONSIBLE FOR DOWNLOADING THEIR OWN COPY OF THE SOLICITATION AND AMENDMENTS. Point of contact: Barbara A. Shadrick; Electronic mail address: bs92y@nih.gov; Fax: 301-480-0241. No collect calls will be accepted. The RFP may be accessed through the Research Contracts Branch Home Page by using the following Internet address: http://rcb.nci.nih.gov/rfp.htm. (0012)

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