DHHS, PHS, CDC, NIOSH, ALOSH, 1095 Willowdale Rd., Morgantown, WV 26505-2888

66 -- SUPRAFUSION APPARATUS, ENVIRONMENTAL CONTROL SYSTEM, WATER BATH STIMULATOR AND ACCESSORIES SOL RP98-012 DUE 022098 POC Brenda Goodwin, 304/285-5882/Contracting Officer, Rex S. Wolfe, 304/285-5883 THIS IS A COMBINED SYNOPSIS/SOLICITATION FOR COMMERCIAL ITEMS PREPARED IN ACCORDANCE WITH THE FORMAT IN SUBPART 12.6, AS SUPPLEMENTED WITH ADDITIONAL INFORMATION INCLUDED IN THIS NOTICE. THIS ANNOUNCEMENT CONSTITUTES THE ONLY SOLICITATION; BIDS ARE BEING REQUESTED AND A WRITTEN SOLICITATION WILL NOT BE ISSUED. This solicitation is issued as Request for Proposal No. RP98-012. This solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 90-46 is being issued unrestricted under Standard Industrial Classification Code 3826 with a size standard of 500 employees. Delivery is desired no later than 30 days after receipt of contract. Offers shall be submitted for one each of the following items or functionally equivalent products which meet the specifications below: (001) Suprafusion 2500 apparatus 18 channel, Brandel #SF2518 or equal; (002) Environmental Control System, Brandel #ECS-118 or equal; (003) Circulating Water Bath, Brandel #CWB-100 or equal; (004) Stimulator and probes, Brandel #ES2-189-55 or equal; and (005) Collection vial ice tray, Brandel #CWT-118. SPECIFICATIONS for SUPRAFUSION APPARATUS: The required apparatus will allow fully programable perfusion of up to 18 independent tissues, will allow electrical stimulation of the tissue, during perfusion and will allow perfusion with up to 6 different and one common reagent. Specific requirements of the apparatus are as follows: -0.30 ml Reaction Chamber volume; -flourosilicon tubing from reagent reservoir to sample collection point; -18 independent reaction chambers to allow simultaneous perfusion of 18 tissues; -- variable speed Peristaltic pump with individual flow adjustment for each reaction chamber or perfusion cell; -collection vial tray with ice cooling capacity; -temperature controlled reaction chamber block to allow perfusion cells to be maintained at variable temperatures to include but not be limited to a range of 40 degrees C to 20 degrees C; -- complete set of 18 (plus two spare) non-conductive probes; -reagent tray for test tubes with provision for reagent gassing with one or two gasses; capability to maintain a uniform adjustable temperature throughout the system including reagent reservoirs, peristaltic pump, reaction chamber block and all transmission tubing; -unit should be fully programable, (without the need for an external computer) for control of such functions as peristaltic pump speed, position of reagent uptake probe, and position of fraction collector delivery needle. For example the unit should be capable of flexible programming to allow reagent to be aspirated from a variety of different types of reservoir vessels and for sample to be collected into a variety of different collection vessels such as vials, eppendorf tubes, 96 well plates, etc. The collection vessel rack and reagent reservoir rack should be sufficiently flexible to allow secure use of various types of vessels. The internal computer of the unit should be able to store at least 10 different programs with capacity for each program to consist of 250 lines of code; -unit should have an RS-232 port so that programs can be transferred to and from the suprafusion unit and some external computer; -unit should have the capability to allow electrical stimulation of the tissue for studies of modulation of stimulated release; -- electrical stimulator should have features of variable output from at least 0 to 200 milliamps per channel with mono or biphasic output, -should be current regulated, -- should include a complete set of wired probes for electrical stimulation, -should allow visual confirmation of the applied current in some kind of graphic display such as a bar graph, -should allow detailed visual examination of output for any single channel, -each cell should be independently regulated and adjustable, -electrical stimulation output should be capable of sine or triangular waveshape. EVALUATION FACTORS: Offers will be evaluated on their ability to meet or exceed the stated specifications and demonstrated past performance on contracts of similar size and complexity to this requirement (include names and addresses of Company/ Government Agency, name and telephone numbers of customer contacts along with contract number, and description of work performed with your offer.) Technical proposals and cost or price are approximately equal in importance. The Government intends to make a single award to the responsible offeror whose proposal conforms to all requirements of the solicitation and is considered the best value to the Government. Offers shall be proposed based on F.O.B. Destination (Morgantown, West Virginia) and the requirements at FAR 52.214.21 "Descriptive Literature" apply. Information provided must clearly demonstrate that all items offered meet or exceed the salient features stated or your offer may be rejected. The following FAR provisions apply to this solicitation: FAR 52.212-1, Instructions to Offerors -- Commercial Items; 52.212-4, Contract Terms and Conditions -- Commercial Items and 52.212-5 Contract Terms and Conditions Required to Implement Statutes or Executive Orders -- Commercial Items. Additionally, the following FAR clauses cited in Clause 52.212-5 are also applicable to this acquisition as follows: 52.222.26 "Equal Opportunity"; 52.222-35 "Affirmative Action for Special Disabled and Vietnam Era Veterans"; 52.222-36 "Affirmative Action for Handicapped Workers"; 52.222-37 "Employment Reports on Special Disabled Veterans and Veterans of Vietnam Era"; 52.225-3 "Buy American Act -- Supplies"; 52.225-18 "European Community Sanctions for End Products." Facsimile submissions are not authorized. Submit the following to DHHS, PHS, CDC, NIOSH, ALOSH, Attn: Brenda Goodwin, 1095 Willowdale Road, Morgantown, WV 26505: (1) original and two copies of a completed SF 1449, signed by an individual authorized to bind the organization; (2) Pricing Schedule for each contract line item and a delivery schedule for each; (3) completed Representations and Certifications -- Commercial Items, FAR 52,212-3; (4) descriptive literature and other information demonstrating compliance with specification for evaluation purposes; and (5) acknowledgment of solicitation amendments, if any. Offers that fail to furnish the required information, or reject the terms and conditions of the solicitation may be excluded from consideration. Information regarding this notice can be obtained from Brenda Goodwin at (304)285- 5882 or by fax at (304) 285-6083. All responsible sources may submit a response, which shall be considered by the Agency. (0030)

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