U.S. Environmental Protection Agency, National Center for Environmental Assessment (MS117), 26 West Martin Luther King Drive, Cincinnati, OH 45268

A -- RISK ASSESSMENT RESEARCH IN WATERBORNE PATHOGEN TO DEVELOP SEVERITY INDICES FOR INFECTION/DISEASE END-POINTS, AND ESTIMATES OF ECONOMIC LOSSES FROM ILLNESS, DISABILITY, AND MORTALITY SOL NCEA-CIN-02 DUE 042098 POC Donna Tucker, FAX No. (513) 569-7475 E-MAIL: Click here to e-mail EPA Contact, tucker.donna@epamail.epa.gov. Requirements -- The United States Environmental Protection Agency, National Center for Environmental Assessment -- Cincinnati Office, is issuing a "Request for Pre-proposals" (RFP) for Cooperative Agreements to conduct both biological and statistical research related to the assessment of human health risk due to pathogen and host factors. Areas of interest include investigations into: human subpopulations (e.g., infants, children, immuno-incompetent, and elderly) waterborne pathogen risk and health outcomes, development of (disease/illness/infection/outcome) severity indices as well as resultant costs, consideration of multi-route exposures, carrier states, and uncertainty factors. The intent is to develop one to three year cooperative agreements on any or all of the announced research areas of interest with the primary purpose of supporting or stimulating human health risk assessment in water-borne pathogen research. Only written requests limited to 10 pages or less describing research proposal will be taken to obtain a detailed RFP solicitation package. Two copies of each pre-proposal must be received by April 20, 1998, and submitted in accordance with the RFP. Pre-proposals will be thoroughly reviewed and evaluated by a peer review panel as set forth in the RFP. Successful pre-proposers will be invited to submit a Competitive Cooperative Agreement Application, including a full and detailed project proposal for funding consideration. Depending on funding availability, the awards are estimated to range from $50,000 to $300,000 total over 3 years. The EPA reserves the right not to make any awards from this RFP. Interested applicants must be eligible to receive Federal Assistance under the Safe Drinking Water Act (SDWA), the Code of Federal Regulations (CFR) Part 30-General Regulation for Assistance Programs, and Part 40- Research and Demonstration Grants. ONLY STATE AND LOCAL GOVERNMENTS, NONPROFIT RESEARCH INSTITUTIONS OF HIGHER EDUCATION, INDIVIDUALS, OR NONPROFIT RESEARCH ORGANIZATIONS ELIGIBLE TO RECEIVE FEDERAL ASSISTANCE UNDER THESE ACTS SHOULD SUBMIT A REQUEST for a preproposal. Proposals from other Federal Agencies are not solicited and will not be accepted. Interested parties may obtain a copy of Solicitation #NCEA-CIN-02 by contacting Donna Tucker, USEPA, National Center for Environmental Assessment -- Cincinnati Office, MS-117, 26 W. ML King Dr., Cincinnati, Ohio 45268, FAX: 513-569-7475. ORAL REQUESTS WILL NOT BE ACCEPTED. (0076)

Loren Data Corp. http://www.ld.com (SYN# 0003 19980319\A-0003.SOL)