National Institute on Drug Abuse, Contracts Management Branch, Parklawn Building, Room 10-49, 5600 Fishers Lane, Rockville, MD 20857

A -- RECEPTOR PROFILING AND/OR COMPOUND LIBRARY SCREENING SOL N01DA-8-8089 POC Patricia W. Mummaugh, Contract Specialist (301) 443-1301 E-MAIL: Internet: "pm69j@nih.gov, pm69j@nih.gov. The National Institute on Drug Abuse is soliciting proposals from qualified organizations having the in-house capability to perform in vitro receptor binding assays on a wide variety of receptor targets, and to perform follow-up binding and functional assays using appropriate in vitro biological systems. Further, the offeror must have the capacity to perform high throughput screening of a large number of compounds at a single receptor or transporter target, with appropriate follow up assays. Proprietary test compounds will be evaluated in established assays, and the resulting data will be utilized by the Cocaine and Opiate Treatment Discovery Programs of the NIDA Medications Development Division. In addition, the successful offeror must indicate possession of current DEA registration for Schedules II-V substances prior to award and apply for Schedule I registration. NIDA anticipates awarding a five-year contract for this procurement. RFP No. N01DA-8-8089 will be available electronically on or about April 24, 1998, and may be accessed through the Internet at the following address: (URL: http://www.nida.nih.gov/RFP/RFPList.html) Please note that the RFP for this acquisition will be streamlined to include only the Work Statement, Deliverables and Reporting Requirements, Special Requirements and Mandatory Qualifications, Technical Evaluation Criteria, and other necessary Proposal Preparation Instructions. All information required for the submission of an offer will be contained in the electronic RFP package. Following proposal submission and the initial review process, offerors comprising the competitive range may be requested to provide additional documentation to the Contracting Officer. Response to the RFP will be due on or about June 8, 1998. Any responsible offeror may submit a proposal which will be considered by the Government. This advertisement does not commit the Government to award a contract. Point of Contact: Patricia W. Mummaugh, Contract Specialist Electronic Mail Address: pm69j@nih.gov Telephone: (301) 443-1301 Fax: (301) 443-7595 (0098)

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