National Cancer Institute, Research Contracts Branch, PSAS, 6120 Executive Blvd, EPS/Room 638, Bethesda, MD 20892-7227

66 -- MOLECULAR IMAGER PC SYSTERM SOL RFQ-80124-NV DUE 050598 POC Debbie Moore, Purchasing Agent 301-402-4509, Todd Cole, Contracting Officer, 301-402-4509 The National Cancer Institute (NCI) intends to procure a Model GS-505 Molecular Imager PC System from Bio-Rad Laboratories, Molecular Biosciences Group, 2000 Alfred Nobel Drive, Hercules, CA 94547 for the National Institute of Neurological Disorders and Stroke (NINDS). The study of receptor regulations requires accurate quantification of the amounts of radioactively labeled proteins as well as of chemiluminescent signals produced in the immunobotting and ribonuclease protections assays. The imager has three different scanning resolutions combined with non-destructive image merging for increased scanning speeds. Low, medium and high resolution scanning allows images to be displayed rapidly at low resolution. The screen can be rescanned at a higher resolution and the scans merged to yield a higher resolution image with no loss of data. The high resolution and dynamic range and should be at least 2000 pixels square with a dynamic range higher than 4 order of magnitude, with a pulse laser scanning to reduce image smearing. The imager must be capable of quantifying both radioactivity from all radioisotopes and chemiluminescence from different sources. The imager shall be directly driven by an external personal computer. The imager shall be capable of being operated by multiple users and be efficiently controlled by a computer that has integrated software that allows quantitative analysis of the data and is compatible with both PC and Macintosh computers and allows data analysis off line. Due to space imitations the dimensions are not to exceed 11 X 25 X 22. It is the Government's belief that these requirements can only be met by Bio-Rad Life Sciences. This is a notice of intent not a request for competitive proposals, however, if an interested party believes they have a instrument that meets the above specifications, they may submit a capability statement To Debbie Moore, 6120 Executive Boulevard, Rockville, MD 20892-7227 by no later than May 5, 1998, 2:00PM EST. Information must be in writing and must contain material in sufficient detail to allow NINDS to determine if the party can perform the requirement. A determination by the Government not to compete this procurement based upon responses to this notice is solely within the discretion of the Government. Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement. (0105)

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