National Institutes of Health, Office of Procurement Management, 6011 Executive Blvd., Rockville, Maryland 20892-7260

66 -- UPGRADE TO AN EXISTING BRUKER NUCLEAR MAGNETIC RESONANCE (NMR) SPECTROMETER POC Sheri Lawson, Contracting Officer on 301/402-3065 or Ed Wilgus, Chief, Acquisitions Branch A/B on 301/402-3070 Under authority of U.S.C. 253(c)(1), FAR 6.302-1 the National Institutes of Health (NIH), Bethesda, Maryland intends to negotiate a contract with Bruker Instruments Inc., 19 Fortune Dr., Billerica, MA 01821. Any response must be received in writing within forty-five (45) business days from the published date of this notice. The intended procurement will be classified under SIC 3826, Laboratory Analytical Instruments with a size standard of 500 employees. The Contractor shall provide an upgrade to an existing nuclear magnetic resonance (NMR) spectrometer as manufactured by Bruker Instruments, Inc. The upgrade shall consist of a single Closed Loop CryoPlatform, an inverse detection 500 MHz CryoProbe for hydrogen observation and carbon decoupling, and a 5mm sample diameter. Each of the two CryoProbes shall come with a Z axis gradient coil, 2H lock channel,, CryoPreAmp and CryoCoupler. (1) The upgrade shall interface and be 100% compatible with an existing AVANCE 500 MHz spectrometer as manufactured by Bruker Instruments, Inc.; (2) The Contractor shall provide all parts and labor to complete the upgrade; (3) The Contractor shall be responsible for any damage that may occur to the existing spectrometer as a result of installation of the upgrade; (4) The first CryoProbe listed shall be a selective inverse 5mm 500 MHz hydrogen-nitrogen Z axis grad CryoProbe. The signal-to-noise ratio shall be 3,000:1 or better for 1% Ethyl Benzene, American Standard of Testing and Measurement standard. Shall produce a hydrogen 90 degree pulse width in 10 microseconds or less. Shall produce a nitrogen 90 degree pulse width in 40 microseconds or less; (5) The second CryoProbe shall be a selective inverse 5mm 500 MHz hydrogen-carbon Z axis grad CryoProbe. The signal-to-noise ratio shall be at least 3,000:1 for 0.15 Ethyl Benzene, American Standard of Testing and Measurement standard. Shall produce a hydrogen 90 degree pulse width in 10 microseconds or less. Shall produce a carbon 90 degree pulse width in 17 microseconds or less; and(6) The Contractor shall provide a Year 2000 Warranty for each hardware, software and firmware product delivered under this contract. The Contractor shall be able to accurately process the data (including, but not be limited to, calculating comparing and sequencing) from, into and between the twentieth and twenty-first centuries and for the Year 2000 and leap year calculations. Nothing in this warranty shall be construed to limit any rights or remedies the Government may otherwise have under this contract with respect to defects other than Year 2000 performance. Information furnished should include enough material to allow the Agency to perform a proper evaluation. Concerns that respond to this synopsis shall furnish concise responses directed specifically to the requirements mentioned above and are invited to submit capability statements in an original plus two (2) copies no later than forty-five (45) business days from the date of this announcement. Source demonstrating the capability to accomplish the above shall supply pertinent information in sufficient detail to demonstrate their ability to perform. Written responses shall include complete description of the services to be provided, containing sufficient technical information to permit agency analysis to establish a bona fide capability to meet the stated requirements as listed above. THIS IS NOT A REQUEST FOR PROPOSAL (RFP). Capability Statements: (a) If MAILING your capabilities through the U.S. Postal Service use the following address: National Institutes of Health, Office of Procurement Management, OA, 6011 Executive Blvd., Room 529Q, MSC 7663 ATTN: Sheri Lawson, Bethesda, MD 20892. (b) If HAND DELIVERING, or using a COURIER SERVICES such as: UPS, Federal Express, etc., use the following City, State, and Zip Code: Rockville, MD 20852. Responses by Facsimile (FAX) will NOT be accepted. SEE: Note 22 (0126)

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