U.S. Environmental Protection Agency, 26 W. Martin Luther King Dr., Cincinnati, OH 45268

A -- REPORT ON ENHANCED EVALUATION OF DISINFECTANT BY-PRODUCT EXPOSURES FOR EPIDEMIOLOGIC STUDIES SOL PR-98-00511 POC Billy Oden (513)487-2126 E-MAIL: U.S. EPA -- Cincinnati Contracts Management Division, Oden.billy@epamail.epa.gov. The U.S. Environmental Protection Agency plans to use simplified acquisition procedures (FAR Part 13) to acquire on a competitive basis services of Water Chemistry Modeling/Environmental Epidemiology Experts, with access to drinking water chemical data bases, and experience in modeling and predicting the occurrence of chemical by-products of disinfection (DBPs) as evidenced by scientific publication in the peer-reviewed literature, to evaluate those data bases for utility in providing enhanced exposure estimation for published epidemiologic studies, to better characterize the type and amount of disinfectant byproducts to which study participants were likely exposed using the guidance developed at a 1994 EPA workshop on this topic; to evaluate the data bases for their utility in planning future epidemiologic studies of exposure to drinking water disinfectants and DBPs; to model DBP exposure for specific geographic areas that have been included in specific epidemiologic studies; and produce high-quality,written reports of these scientific activities. This effort will involve developing a written report (with oral presentation to EPA) describing the geographic areas and studies to be evaluated and availability of existing data bases suitable for providing the necessary drinking water chemical exposure information; 2) Written report describing and summarizing the abstracted and analyzed exposure information for the existing epidemiologic studies and the specifics of the development and application of the predictive chemical DBP models and a description of the available interim results; and, 3) Written report (with oral presentation to EPA) describing the utility of the existing exposure data bases for providing sufficient water quality data to recommend where future epidemiologic should be conducted, based on the type and nature of chemical DBPs likely to be formed. Requests for Quotations will be provided to those entities that submit an e-mail request to the address below. Telephone requests will not be honored. See Note 1. (0139)

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