Loren Data Corp.

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COMMERCE BUSINESS DAILY ISSUE OF JUNE 15,1998 PSA#2116

Centers for Disease Control and Prevention (CDC), Procurement & Grants Office, Contracts & Purchases Branch, 255 East Paces Ferry Rd., NE, Rm 419, Atlanta, GA 30305

B -- COLLECTION OF BLOOD SPECIMENS FROM HEALTH CARE WORKERS & SOURCE PATIENTS FOLLOWING OCCUPATIONAL EXPOSURES TO HIV-INFECTED BLOOD. SOL 98S166(N) DUE 073098 POC Lorenzo J. Falgiano, Contract Specialist, (404) 842-6786 The Centers for Disease Control and Prevention contemplates awarding a contract for collecting blood specimens from health care workers and source patients following occupational exposures to HIV-infected blood. The purpose of this study is to 1) assess antiretroviral drug resistance of patients infected with human immunodeficiency virus (HIV) who are source patients for percutaneous injuries to health care workers (HCWs) to determine the impact that resistance may have for the post-exposure prophylaxis (PEP) regimen recommended for the HCW in US Public Health Service (PHS) guidelines; 2) develop a greater understanding of the prevalence of factors in source patients that may influence the risk of transmission of HIV, including drug resistance and viral load; and 3) examine various aspects of the immune response of HCWs who sustain percutaneous injuries to HIV infected blood. The successful offeror will submit to CDC, 10-20 specimens from source patients involved in occupational percutaneous exposures to HIV-infected blood. Also, specimens from 6-8 health care workers involved in percutaneous exposures with a risk of HIV transmission, and 2-3 health care workers (i.e., "controls") involved in percutaneous exposures to blood from HIV negative source patients collected at baseline and at specified times during postexposure follow-up. The successful offeror will also be required to provide HIV-infected and related data to accompany the required specimens. The period of performance will be 12 months from the contract award date with one (12) month option period. The schedule issue date is approximately June 29, 1998. No telephone requests will be accepted; only written requests for this solicitation will be honored. Requests should cite RFP Number 98S166(N). (0162)

Loren Data Corp. http://www.ld.com (SYN# 0018 19980615\B-0008.SOL)


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