REQUEST FOR INFORMATION; POTENTIAL EPIDEMIOLOGY STUDY ON HEMOCHROMATOSIS. For planning purposes for a potential future epidemiology study on hemochromatosis, the National Heart, Lung, and Blood Institute requests information from primary health care providers/health maintenance organizations. Interested organizations with patient/participant populations of 100,000 or more adults aged 25 or older are asked to submit the following information: 1. Total numbers of patients, and numbers stratified by gender, race/ethnicity and 10 year age groups, receiving routine blood draws for health screening purposes such as cholesterol monitoring; 2. Inventory of clinical assessments and laboratory assays included during these screens; 3) Direct and total costs for performing transferrin saturation and serum ferritin assays; 4. Direct and total costs, including percent effort, for a research assistant to administer informed consent and a 20 minute questionnaire in conjunction with routine blood draw; 5. Estimate of numbers of patients over age 25 by race/ethnicity likely to agree to addition of transferrin saturations to their routine screening as part of a research protocol during a two year recruitment period. Please provide the requested information within ten (10) days after the date this notice is published. Responses by facsimile, if legible, will be accepted; otherwise, please submit four(4) copies of the requested information to the individual listed above. The facsimile number is (301)480-3430 and the telephone number is (301) 435-0353. E-MAIL: Request for Information;Hemochromatosis., 1o17f@nih.gov.

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