National Cancer Institute, Research Contracts Branch, PSAS, 6120 Executive Blvd, EPS/Room 638, Bethesda, MD 20892-7227

66 -- NITRIC OXIDE ANALYZERS SOL RFQ80152-NS DUE 070898 POC Patricia Haun, (301) 496-8613 This is a combined synopsis/solicitation for commercial items, prepared in accordance with the format in FAR 12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation, and a separate written solicitation will not be issued. This solicitation, No. RFQ80152-NS will include all applicable provisions and clauses in effect through FAR FAC 97-04. The acquisition is being made in accordance with the test program for using simplified procedures for certain commercial items authorized in FAR 13.6. The Standard Industrial Code is 3827 and the business size is 500 employees. However, the solicitation is not set-aside for small businesses. General Requirements: The National Cancer Institute is soliciting quotations for two (2) Nitric Oxide Analyzers, each to include Nitric Oxide Data Analysis Software; a pentium laptop PC computer; gas sampling interfaces; an accurate breath kit; an odor filter; and an NOA calibration kit. In addition, one (1) radical purger shall be required for use with either Nitric Oxide Analyzer. HARDWARE REQUIREMENTS: The analyzers shall include a detector, vacuum pump, an operating manual, and one year warranty for each detector. The Nitric Oxide Analyzers shall have the following outputs: an analog, digital printer; and an on-board 512 KB RAM Card that is expandable for data storage. In addition, the analyzers shall possess the following: 1) A response time of 200 milliseconds to 90% full scale 2) A display -- backlit LCD in ppm/ppb or mV 3) An oil-filled transformer (for Ozone Generation) 4) PMT cooled to -10 Celsius for optimal chemiluminescence sensitivity 5) An oil-filled vacuum pump with a vacuum capability of 0.75 x 10-4 Torr, a flow capacity of 3.5cfm, and an operating sound level not to exceed 60dB or better. 6) Liquid sampling capability of one (1) picomole minimum detection limit to 100 nanomoles; a sample size of a few microliters up to 5ml; and the capability to analyze nitric oxide, nitrite, and/or nitrate in a variety of biological samples. 7) Gas sampling of less than 1 ppb minimum detection to 500 ppm NO; a 200 millisecond response time; a 10 to 300 mL minimum flow rate; and the capability of breath by breath analysis in animals (including humans) to measure pressure and nitric oxide simultaneously and in real time. 8) Automatic tracking of consumables and routine maintenance. 9) A purge vessel, inclusive of a glass hot water jacket that completely surrounds the sample to provide complete and even distribution of heat to the reaction chamber; a drain stopcock; and a small reaction cell volume to provide a minimum of 10 mL dead space resulting in optimal peak detection and minimal data transition time. 10) A pentium laptop PC computer with a minimum of 16 MB RAM and a 1.0 GB Hard Drive or greater. SOFTWARE REQUIREMENTS: The Nitric Oxide Data Analysis Software shall possess the following characteristics: 1) Real-time graphical display of NO signals 2) Adjustable graphical view zooming and panning to enable the graft to shift vertically or horizontally within the graph window (x and y axis auto-scale) 3) Flexible peak integration to enable the user to adjust peak start and stop settings and to allow the user to adjust the threshold and peak-width settings 4) Automatic preparation of calibration curves, including the creation of new calibrations, the adding of data to an existing calibration, and the ability to print calibration curves 5) Automatic calculation of sample concentrations to identify liquid samples by name as injection takes place and to input injection volumes to provide greater flexibility 6) Automatic calculation of sample concentrations within the collection process to add results to existing results files or to create a comprehensive results file (previous and updates) and to print the file 7) Automatic calculation of sample concentrations to enable the mean, standard deviation and %RSD of gases for each subject to be determined and the results sent directly to the printer or saved on disk8) Flexible technique to establish the user's definable breath pressure and the exhaled breath flow rate 9) Flexible data collection of up to 10 NO plateaus per subject, computer calculated or user- adjustable setting of NO plateau, and the ability to print the NO plateau 10) Storage of raw data files, ability of results tables and callibration curves to be stored in tab delimited text files to allow direct input into spreadsheet or statistic programs. Offerors must provide a descriptive literature, warranties, and/or other materials that demonstrate that their offer meets the foregoing requirements. The purchase order will be issued to the responsible offeror with the lowest-price that fully meets the requirements of the solicitation. Furthermore, delivery shall be FOB Destination or FOB Origin with transportation insurance provided by the vendor, and inside delivery shall be provided to 10/B3B69 within 30 days after receipt of the order. The Government shall reimburse those vendors with standard commercial terms of FOB Origin for all transportation insurance. This solicitation incorporates the provisions at FAR 52.212-1, INSTRUCTIONS TO OFFERORS-COMMERCIAL ITEMS, and at FAR 52.212-3, OFFEROR REPRESENTATIONS AND CERTIFICATIONS-COMMERCIAL ITEMS. The latter provision includes the DUNS Number Addendum. The resulting contract will incorporate the requirements of the Clause at 52.212-4, CONTRACT TERMS AND CONDITIONS-COMMERCIAL ITEMS, and the requirements contained in paragraphs (a) and (d) of the clause at FAR 52.212-5, CONTRACT TERMS AND CONDITIONS REQUIRED TO IMPLEMENT STATUTES OR EXECUTIVE ORDERS- COMMERCIAL ITEMS -- DEVIATION FOR SIMPLIFIED ACQUISITIONS. The Contract will also incorporate the following FAR clauses cited in paragraphs (b) and (c) of the latter clause: FAR 52.222-26, EQUAL OPPORTUNITY; FAR 52.222-35, AFFIRMATIVE ACTION FOR SPECIAL DISABLED AND VIETNAM ERA VETERANS; FAR 52.222-36, AFFIRMATIVE ACTION FOR HANDICAPPED WORKERS; FAR 52.222-37, EMPLOYMENT REPORTS ON SPECIAL DISABLED VETERANS AND VETERANS OF VIETNAM ERA; and FAR 52.225-3, BUY AMERICAN ACT -- SUPPLIES. Offerors must submit a complete copy of Representations and Certifications, including the provision for the DUNS Number (FAR Clause 52.204-6), with their offer. Offers are due 15 days after the publication date of this notice by 3:30 p.m. EST. Facsimile submissions are permissible with follow-up of an original copy. Offers must be in writing and should be submitted as follows: 1) a completed SF 18 or SF 1449, signed by an individual authorized to bind the organization; 2) a Schedule of the offered materials containing pricing and a delivery schedule; 3) completed Representations and Certifications-Commercial Items, with DUNS Number addendum; 4) descriptive literature indicating that the offer meets the stated requirement; 5) acknowledgment of amendments, if any. The Representations and Certifications or other cited provisions and clauses may be obtained from Patricia Haun, Purchasing Agent, on (301)402-4509 or by fax on (301)402-4513. Offers and related materials must be submitted to Patricia Haun at the listed address or the fax number above. Offers that fail to furnish the required information or reject the terms and conditions of the solicitation may be excluded from consideration. Please cite the solicitation number on your offer. Posted 06/24/98 (0175)

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