National Cancer Institute, Research Contracts Branch, PSAS, 6120 Executive Blvd, EPS/Room 638, Bethesda, MD 20892-7227

66 -- GENE CHIP EXPRESSION ANALYSIS SYSTEM SOL RFQ80156(NR) DUE 072798 POC Marsha Gorham, Purxhasing Agent (301)402-4509, Todd Cole, Contracting Officer The National Cancer Institute plans to procure two Gene Chip Expression Analysis Systems from Affymetrix Inc., 1145 Sonora Court, Sunnyvale, CA 94086. This is a combined sole source synopsis/solicitation for Commercial Items prepared in accordance with the format in the Federal Acquisition Regulation (FAR) 12.6, as supplemented by additional information included in this notice. This announcement constitutes the only solicitation and a separate written solicitation will not be issued. RFQ80156 is issued as a request for quotation. This acquisition is set-aside for small businesses. The Standard Industrial Classification Code is 3826 and the business size standard is 500. Requirement: Each system shall be individually capable of the following: 1. Shall combine solid phase chemical synthesis with photo lithographic fabrication techniques. 2. Shall be capable of scanning high density arrays of sequences which can be accessed simultaneously through automated con-focal argon laser interrogation. 3. Shall include image processing software capable of processing information from the high density arrays in 30 minutes or less. 4. The software shall be able to gather experimental information from the operator through dialog boxes. 5. The software shall be able to generate real-time image of fluorescence intensity information from the probe array and store it in a raw data file. 6. Shall have the capability to probe arrays with as many as 400,000 different probes. 7. Shall be able to scan a 1.28cm X 1.28cm probe array labeled with a single dye in 5 minutes. 8. The software shall automate the control of both the scanner and the fludics station. 9. The software shall acquire and average hybridization intensity data as well as print image, sequence and report files. 10. The Contractor shall provide a year 2000 warranty for each hardware, software, and firmware product delivered under this contract. The Contractor shall be able to accurately process date data (including, but not limited to, calculating, comparing, and sequencing), from, into, and between the twentieth and twenty-first centuries and the Year 2000 and leap year calculations. Nothing in this warranty shall be construed to limit any rights or remedies the Government may otherwise have under this contract with respect to defects other that Year 2000 performance. This notice of intent is not a request for competitive proposals, and Affymetrix Inc. is the only known source to NCI that can meet the requirement. However, all responsible sources that believe that they can meet the requirement may submit offers. All offers must be received in the Contracting Officer on or before July 27, 1998 at 10:00AM EST. (Within 17 days days after the date of pubication). Two purchase orders (one for each system) will be issued based on this solicitation. Delivery shall be FOB Destination or FOB Origin with transportation insurance provided by the vendor with inside delivery within 90 days after receipt of order. One system shall be delivered to Advanced Technology Center/NCI Sequencing & Genotyping Facility, 8717 Grovemont Center, Gaithersburg, Maryland 20877 and the other system shall be delivered to NIH, 9000 Rockville Pike, Building 41, Room B403, Bethesda, Maryland 20892. The Government will reimburse the vendor for transportation if its standard commercial terms are FOB Origin. This solicitation and the incorporated provisions and clauses are those in effect through Federal Acquisition Circular 97-05 This solicitation incorporates the provisions at FAR 52.212-1, INSTRUCTIONS TO OFFERORS- COMMERCIAL ITEMS and at FAR 52.212-3, OFFEROR REPRESENTATIONS AND CERTIFICATIONS -- COMMERCIAL ITEMS. The latter provision includes the DUNS NUMBER ADDENDUM. The resulting contract will incorporate the requirements of the clause at FAR 52.212-4, CONTRACT TERMS AND CONDITIONS -- COMMERCIAL ITEMS, and the requirements contained in paragraphs (a) and (d) of the clause at FAR 52.212-5, CONTRACT TERMS AND CONDITIONS REQUIRED TO IMPLEMENT STATUES OR EXECUTIVE ORDERS COMMERCIAL ITEMS-DEVIATION FOR SIMPLIFIED ACQUISITIONS. The contract will also incorporate the following FAR clauses cited in paragraphs (b) and (c) of the latter clause: FAR 52.222-26, EQUAL OPPORTUNITY; FAR 52.222-35, AFFIRMATIVE ACTION FOR SPECIAL DISABLED AND VIETNAM ERA VETERANS; FAR 52.222-26, AFFIRMATIVE ACTION FOR HANDICAPPED WORKERS; FAR 52.222-37, EMPLOYMENT REPORTS ON SPECIAL DISABLED VETERANS AND VETERANS OF VIETNAM ERA,; and FAR 52.225-3, BUY AMERICAN ACT -- SUPPLIES. Full text copies of these representations and certifications or other cited provisions and clauses may be obtained from Marsha Gorham on (301)402-4509. Affymetrix is the only source known to NCI that can meet the above requirement. However, if any interested party believes it can meet the above specifications it may submit an offer. Offers must be submitted in writing on an SF 18 or SF 1449 with a completed Schedule of Offered Supplies/Services. Offers must be accompanied by a completed Representations and Certifications Commercial Items, with DUNS Number addendum, signed by an authorized representative of the offeror. Offers must also be accompanied by descriptive literature, warranties, and/or other information that demonstrates that the offeror meets the foregoing requirements. The contract will be awarded to the offeror with the lowest- price offer that fully meets the requirements of the solicitation. Submit offers to Marsha Gorham at the address listed in this notice. Please reference the solicitation number RFQ80168 on your offer. No collect calls will be accepted. Posted 07/10/98. (0191)

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