DIRECTOR, USAMRAA, 820 CHANDLER ST, FORT DETRICK MD 21702-5014

A -- STUDIES SUPPORTING THE MEDICAL CHEMICAL DEFENSE PROGRAM SOL DAMD17-98-R-0014 DUE 100198 POC Contract Specialist Cheryl A. Lowery (301) 619-7150 (Site Code DAMD17) The U.S. Army Medical Research and Materiel Command has as one of its major responsibilities the mission of establishing and maintaining an effective medical chemical defense posture for our Armed Forces. To augment the Army's in-house scientific endeavors at improving the survivability of soldiers in chemically-contaminated environments, a Request for Proposals (RFP) will be issued to solicit a contractor to answer and validate basic, applied, and developmental biomedical questions critical to providing medical countermeasures against known and emerging chemical threats. The RFP work statement requires writing study protocols and conducting tests for potential decontamination and protective systems, as well as antidotal and therapeutic compounds against chemical agent contamination. Studies will involve in vivo and in vitro experiments, animal models, alternatives to animal models, and comprehensive benchtop procedures using chemical surety materiels (CSM) and other hazardous chemicals. Protocols, studies, and reports shall comply with Good Laboratory Practice (GLP) and current Good Manufacturing Practice (cGMP) guidelines, the Guidebook of Performance Standards for Operation of a Research, Development, Test and Evaluation CSM Laboratory, and other applicable U.S. Government regulations. The resultant contractor must be able to conduct multiple tasks simultaneously and to adjust to rapidly changing priorities. The government plans to award a three-year indefinite delivery (cost-reimbursement) contract with a provision for two one-year options. RFP No. DAMD17-98-R-0014 is planned for release approximately 15 August 1998. Requests for the RFP package must be in writing and forwarded to the U.S. Army Medical Research Acquisition Activity (USAMRAA), ATTN: Ms. Cheryl A. Lowery), 820 Chandler Street, Fort Detrick, MD 21702-5014. All requests must reference RFP No. DAMD17-98-R-0014. Faxed requests will be accepted and must be forwarded to Area Code (301) 619-4084. Proposals will be due within 45 days after the RFP is issued. (If the RFP package was requested previously in response to the 13 May 1998 CBD Announcement, there is no need to submit another request). Posted 07/23/98 (I-SN227578). (0204)

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