U. S. Environmental Protection Agency, Contracts Management Division (MD-33), Attn: ORDSC, Research Triangle Park, NC 27711

R -- CONFERENCE SUPPORT FOR BIOMATHMATICAL MODELING OF RISKS OF DISINFECTION BY-PRODUCTS SOL XE0072 POC David A. Donnelly Jr., Contract Specialist, 919-541-7888/Phyllis Roberts/Contracting Offficer WEB: Click here to visit the site that has information about, http://www.epa.gov/oam/rtp-cmd. E-MAIL: Click here to contact the Contract Specialist via, donnelly.dave@epamail.epa.gov. The U.S. Environmental Protection Agency (U.S. EPA) is seeking qualified sources to provide conference support services for a Workshop on Biomathematical Modeling of the Risks of Disinfection By-Products. The workshop will focus on dose-response research to evaluate the cancer and non-cancer effects of Disinfection By- Products (DBPs) in drinking water. An important part of this research is to develop mechanistic models of toxic effects of DBPs to reduce the uncertainties in the predictions of human health risks for DBPs. The purpose of the workshop is to 1) Define the existing state of biomathematical modeling support of DBP risk assessment; (2) Identify key areas where models and information needed to produce or test them are deficient; and (3) Specify the most beneficial strategy for producing the suite of models needed to predict the relationship between exposure and risk for DBPs and mixtures thereof. The workshop shall focus on meeting the above goals and shall result in the writing of a detailedresearch strategy that will specify the modeling tasks that need to be carried out to be able to predict the relationship between exposure and risk for individual DBPs and mixtures of DBPs. The contractor shall plan, organize, implement, and provide a written report on the workshop. The workshop shall not exceed two days. The contractor shall establish a Guiding Committee from among scientists conducting relevant research in DBPs or related areas, and will perform all steps necessary to plan a workshop to meet the goals and time frame. The Guiding Committee shall be selected from scientists in the Research Triangle Park and from within a 100 mile radius of Research Triangle Park, NC to represent a balance among the academic, governmental, and private sectors, and will have primary responsibility for selecting workshop participants and determining the workshop agenda. The contractor shall perform all tasks necessary to conduct the workshop, including inviting participants, providing an appropriate venue, providing for the necessary equipment, and providing for production of a summary of the deliberations of the workshop participants. The contractor shall prepare a written final report of the workshop. The period of performance is from the date of award through September 30, 1999. This acquisition is a small business set-aside with a SIC code of 8999 with a size standard of $5M in average annual receipts over the preceding three fiscal years. The EPA anticipates awarding a firm fixed-price purchase order. The Request for Quotation (RFQ) is expected to be issued on or about 8/11/98 with quotations due approximately 8/25/98. All responsible sources must respond within 15 days from the date of this announcement. Faxed requests will be honored, including faxed quotations. Telephone requests will not be honored. Submit requests to the attention of David Donnelly. The fax number is (919) 541-4273 or (919) 541-1075. See Numbered Note(s) 1 and 26. Posted 07/27/98 (W-SN228659). (0208)

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