Loren Data Corp.

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COMMERCE BUSINESS DAILY ISSUE OF AUGUST 20,1998 PSA#2163

NCI Frederick Cancer Research and Development Center (NCI-FCRDC), P.O. Box B, Frederick, Maryland 21702-1201

Z -- RENOVATE EXISTING BUILDING 325 INTO A FACILITY FOR BULK FERMENTATION OF PARENTERAL DRUGS UTILIZING CGMP FINISHES, WORKSCOPES, PIPING AND HVAC SOL H98-258 DUE 091598 POC Point of contact: Thomas L. Danver, Sr. Contracts Specialist, 301-846-5422 E-MAIL: Research and Construction Contracts, tdanver@mail.ncifcrf.gov. RENOVATE EXISTING BUILDING INTO A FACILITY FOR BULK FERMENTATION OF PARENTERAL DRUGS UTILIZING cGMP FINISHES, WORKSCOPES, PIPING AND HVAC. SAIC Frederick, the operations and technical support contractor for the National Cancer Institute (NCI), Frederick Cancer Research and Development Center (FCRDC) has completed design for the renovation and upgrade to an existing building. This is a 4200 SF (Gross), single story masonry and steel structure owned by NCI at Fort Detrick in Frederick, Maryland. The work includes, but is not limited to, structural pressure grouting of existing foundation, partial demolition of walls, raising of the roof with installation of new attic mechnical area, installation of new roof top air handling units, installation of new domestic water main entrance, replacement of existing and installation of new plumbing, HVAC and electrical systems, upgraded and refurbished reverse osmosis, water for injection and clean steam systems, BioHazard Large Scale Level 2 fermentation and Class 10,000 and 100,000 laboratories, tissue culture lab, lab support areas and automated building control systems. The building shall be enhanced architecturally to cGMP type surfaces with replaced or repaired flooring, doors, wall surfaces and roofing. Construction time frame is estimated to be six (6) months, including contractor testing and acceptance. Potential contractors will be required in their proposal to show direct experience of company and key personnel in successfully completing at least one of the following: (a) Facilities for Bulk Fermentation of Parenteral Drugs, (b) BL3 or BL4 Laboratories as well as Class 10,000 or Class 100,000 Clean Rooms, or (c) Pharmaceutical Processing Facilities containing sanitary piping and aseptic production equipment. Interested contractors will be required in their proposal to provide evidence of having successfully built at least one such Facility in the last five (5) years where the construction cost was $3,000,000.00, or more, with evidence that those facilities were tested, approved and accepted. Contractors shall provide a statement of project management capabilities and techniques with resumes of relevant/key personnel, who shall be made available for the duration of the project. Interested prime contractors should fax/e-mail letters of interest to Thomas L. Danver at 301-846-5414/tdanver@mail.ncifcrf.gov. Posted 08/18/98 (W-SN238552). (0230)

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