U.S. Environmental Protection Agency, Program Contract Service Center (3803R), 401 M Street, SW, Washington, DC 20460-0001

R -- EXPOSURE ASSESSMENT FOR TOXIC SUBSTANCES SOL PR-HQ-98-14374 DUE 102798 POC Ms. Felicia M. Williams, Contract Specialist, 202-564-4768 and Mr. John J. Nanartowicz III, Contracting Oficer, 202-564-4756 WEB: Exposure Assessments for Toxic Substances, http://www.epa.gov/oamhpod1. E-MAIL: Contract Specialist, williams.felicia@epamail.epa.gov. THIS REQUIREMENT WILL BE PROCURED UTILIZING FULL AND OPEN COMPETITIVE PROCEDURES!! The Environmental Protection Agency (EPA) under the Office of Pollution Prevention and Toxics (OPPT), Economics, Exposure and Technology Division (EETD), in Washington, D.C., has a need to provide exposure assessments and the relevant information necessary for EPA to develop exposure assessments in order to fulfill the requirements of the Toxic Substance Control Act (TSCA), the Pollution Prevention Act, and any Executive Order or other legislative requirements. Simply stated, an exposure assessment is the combination of data on the source, location, and characteristics of the chemical or biological agent with information on the location and habits of populations. The development of an exposure assessment, however, may range from a streamlined, integrated process for ranking and prioritizing chemical and biological agents on the basis of relative risk to a very comprehensive, complex and detailed analysis. It may include the development and refinement of models which are then used to predict exposure of defined populations to a variety of chemicals. It may require monitoring studies to collect much-needed field data to define exposure with more certainty. It involves the constant study and search for information on the fate and transport properties of chemicals and their physical, chemical and biological properties. When models are used to predict exposure, assumptions are often needed to define the scenario to be modeled and data are needed to characterize the scenario and the chemical or biological agent of interest. The more credible the assumptions and the more complete and current the supporting data, the better the exposure assessment. Consequently, to fulfill this requirement the contractor shall provide information to the Government sufficient to support these modeling exercises and shall refine and update analytical tools necessary to accomplish this objective. When monitoring or laboratory studies are required, the contractor shall develop a sampling plan, a quality assurance project plan and shall make all necessary arrangements to assure the success of the monitoring study. The contractor shall provide information to the Government sufficient to support the development of exposure assessments for situations that are not necessarily specific to any one chemical. This involves the development of innovative and creative procedures to assess exposure to clusters of chemicals, chemicals contained in marketable products and genetically engineered microorganisms defined to be chemicals for the purposes of the Toxic Substance Control Act. Further, the contractor shall provide assessments either for existing chemicals where the values obtained are estimates of actual exposure or for new chemicals (or projected changes in production/use/disposal patterns of existing chemicals), where the values obtained are estimates of potential future exposures. For copies of the complete Request for Proprosal, please visit the U.S. EPA Website at http://www.epa.gov/oamhpod1/oppts_grp/dc9814374/index.htm, or E-mail the Contract Specialist at "williams.felicia @epamail.epa.gov" for a copy of the solicitation package. Due to the anticipated large volume of interest, we will be unable to return phone calls for this procurement. The Contract Specialist can be reached at 202-564-4768. You may be able to retrieve a copy of the request for proposal package on or about September 21, 1998. NOTE: An original plus five (5) copies of all proposals should be delivered on or before the closing date of the solicitation to the following address (fax/e-mail copies will not be accepted): U.S. EPA, 401 M Street S.W., Mail Code 3803R, Washington, D.C. 20460 Attn: Ms. Felicia Williams -- -HAND CARRY ADDRESS -- - 1300 Pennsylvania Avenue, N.W., Bid and Proposal Room 6th floor, Washington, D.C. 20003 Attn: Ms. Felicia Williams. Posted 09/02/98 (W-SN244776). (0245)

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