National Cancer Institute, Research Contracts Branch, PSAS, 6120 Executive Blvd, EPS/Room 638, Bethesda, MD 20892-7227

66 -- INSTRUMENTS & LABORATORY EQUIPMENT SOL RFQ-NCI-80234 DUE 092398 POC Cynthia Brown, Purchasing Agent, 301-402-4509, Todd Cole, Contracting Officer The Developmental Therapeutics Program (DTP), Division of Cancer Treatment Diagnosis (DCTD), National Cancer Institute, National Institutes of Health plans to procure a Quali-Fill Oil and Paste Filling Machine with additional changeable parts from Schaefer Technologies, Inc., 4251 North Shadeland Avenue, Indianapolis, IN. 46226. Solicitation number RFQ-NCI-80234. DTP requires a ring style capsule filling attachment for a Parke Davis Model 8 machine capable of filling liquids, semisolids, and pastes into hard gelatin capsules in order to design and develop dosage forms for anticancer and anti-AIDS drugs for use in the toxicologic studies and NCI- sponsored clinical trials. This equipment will enable us to develop the formulations that can rapidly enter the agents into clinical trials and save patients' lives. The National Cancer Institute currently has a Parke Davis Model 8 semiautomatic capsule filling machine that rectifies, separate, fills powder, and joins the hard gelatin capsules. The Quali-Fill oil and Paste Filling Machine is an attachment to Parke Davis 8 that is capable of: 1) filling oily and paste like oral formulations into hard gelatin capsules. 2) The machine is easily to disassemble, wash, and reassemble. 3) The filling amounts can be easily adjusted by turning the handle to a desired value. 4) All parts are made of stainless steel for durability and cleaning purposes. 3) the machine can also accommodate filling capsules of sizes 1, 2, 3, and 4 without changing parts. The required change part will enable the filling of size 0 and 00, as well. Since the Quali-Fill Oil and Paste Filling Machine (with additional change parts) from Schaefer Technologies, Inc. is compatible to the Parke-Davis, it is the only source known to NCI that can meet the above requirements. If any interested party believes it has a compatible machine and it can meet the automatic filling requirements and standards herein, it may submit a statement of capabilities. The statement of capabilities and any other information furnished must be in writing and must contain material in sufficient detail to allow NCI to determine if the party can perform this requirement. Capability statements must be received in the contracting office by 3:00 p.m. EST, on Sept. 25, 1998. If you have any questions, please contact Cynthia Brown, Purchasing Agent on 301-402-4509. A determination by the Government not to compete this proposed requirement based upon responses to this notice is solely within the discretion of the Government. Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement. NOTE: Delivery shall be made F.O.. Destination, inside delivery no later than 60 days after receipt of order to the Dr. Ronald Poust, University of Iowa, College of Pharmacy, G20 Pharmacy Building, Iowa City, IA 52242. Posted 09/04/98 (W-SN246134). (0247)

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