National Institutes of Health, National Institute of Allergy and Infectious Diseases, Contract Management Branch, Solar Bldg., Room 3C07, 6003 Executive Blvd. MSC 7610, Bethesda, MD 20892-7610

A -- COLLABORATIVE NETWORK FOR CLINICAL RESEARCH ON IMMUNE TOLERANCE: ANNOUNCEMENT OF DRAFT PROJECT REQUIREMENT SOL NIH-DAIT-NIAID-00-07 DUE 101498 POC Rosemary McCabe Hamill, Contracting Officer, (301) 496-0384 The NIAID Division of Allergy, Immunology and Transplantation has developed a draft contract solicitation designed to establish the Collaborative Network for Clinical Research on Immune Tolerance, beginning in FY 2000. An Announcement of the requirements of the draft solicitation, and a request for comments, are located on the NIAID web site at: http://www.niaid.nih.gov/publications/immune/rfp1.htm, titled: "Collaborative Network for Clinical Research on Immune Tolerance: Announcement of Draft Project Requirement." This draft solicitation is a direct outgrowth of the Division's scientific planning efforts over the past year to develop a broad-based plan to accelerate research on immune tolerance, including research in the clinical setting. These efforts have included: 1. Development of a long-range plan for basic, pre-clinical and clinical research on immune tolerance; 2. Establishment of an expert panel to review and provide recommendations on the scope, timeliness and design of the research plan; and 3. Establishment of a second expert panel to provide recommendations on ethical issues in clinical trials of transplant tolerance. The NIAID Plan for Research on Immune Tolerance, as well as the recommendations of these two expert panels, are located on the NIAID web site at: http://www.niaid.nih.gov/research/dait.htm, under the document title: "NIAID Plan for Research on Immune Tolerance." Please note that proposals are not being solicited at this time. The Announcement is intended to solicit comments and recommendations on the entire draft solicitation, including the Statement of Work, the Technical Evaluation Criteria, and the Reporting Requirements, in order to determine the level of interest and assure that the requirements will meet the objectives of this research program. The NIAID is requesting that comments, questions and recommendations be submitted to Rosemary McCabe Hamill, NIAID Contracting Officer for this initiative, by October 14, 1998. Please remember that all responses should be directed in writing by U.S. mail or electronic mail to: National Institutes of Health National Institute of Allergy and Infectious Diseases Attention: Rosemary McCabe Hamill, Contracting Officer Contract Management Branch (Ref. NIH-DAIT-NIAID-00-07) 6003 Executive Boulevard, Solar Building, Room 3C03 Rockville, Maryland 20852 E-mail: rh26v@nih.gov Posted 09/22/98 (W-SN252685). (0265)

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