National Institutes of Health; Clinical Center Support, DSSC, OPM 6011 Executive Blvd., Suite 538, Bethesda, MD 20892-7663

Q -- PROFESSIONAL POSITRON EMISSION TOMOGRAPHY (PET) RADIOCHEMISTRY, RADIOPHARMACY, BIOMEDICAL ENGINEERING, AND CYCLOTRON OPERATION VICES SOL CC-98-01 POC Molly Eng, Contracting Officer, 301/443-7810. The National Institutes of Health, Clinical Center, has a requirement for professional positron emission tomography (PET) radiochemistry, radiopharmacy, biomedical engineering, and cyclotron operation services in support of its 350-bed research hospital. Solicitations will be accepted from commercial non-profit, and educational organizations. Offerors shall provide professional staff, materials, equipment, and facilities (not otherwise provided by the Government). Services required include but are not limited to the following: 1) Radiochemistry -- a) preparation of radiopharmaceuticals using the chemical separation techniques including HPLC and TLC chromotographic techniques), standard chemical laboratory instruments and radiochemical apparatus (ionzation meters, radioisotopes calibrators and multichannel analyzers); b) develop and implement new techniques for the production and quality control of new or potential radioligands; and c) perform quality control analyses of IND radiopharmaceuticals. 2) Radiopharmacy -a)dispense radiopharmaceuticals for patients undergoing PET studies; b) quantify radioactivity measurement in blood samples; and c) perform quality control activities. #3) Biomedical Engineering -- a) design, configuration, implementation, testing and maintenace of systems involving electronic components, radiation detectors, and computer interfaces for collecting and processing research data in conjunction with PET studies; b) design, implement, test and maintain new software programs which include new PET data acqusition techniques, post-processing algorithms, image reconstruction algorithms, etc.; amd c) solve problems associated with day-to-day operation of PET scanners and associated with hardware and software. 4) Cyclotron operations -- a) provide vital expertise for reliable and efficient clyclotron operations; b) develop cyclotron equipment and targetry to meet new needs or enhance productivity and reliability; c) plan equipment and maintenance and upgrades to allow maximum cyclotron use and minimum down-time. Participate in the quality assurance program and the total quality management process as required by the PET staff. NIH will award a one-year contract with 4 options at 12 months each released on or about April 1, 1999. Performance will be accomplished at NIH, Bethesda, MD. Solicitation will be released on or about October 30, 1998. All responsible sources may submit a proposal which will be considered by the National Insitutes of Health, Clinical Center Support. Request for solicitation must be in writing. Posted 10/06/98 (I-SN259373). (0279)

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