National Cancer Institute, Research Contracts Branch, ESS, Executive Plaza South, Rm. 620, 6120 Executive Blvd., MSC 7224, Bethesda, MD 20892-7224

B -- INTERDISCIPLINARY STUDIES OF GENETIC AND ENVIRONMENTAL CAUSES OF CANCER SOL N02-CP-91026-50 DUE 012599 POC Karen L. McFarlane, Contracting Officer, (301) 496-8611 WEB: Acquisition Management Branch Home Page, http://amb.nci.nih.gov/rfp.htm. E-MAIL: Karen L. McFarlane, km63k@nih.gov. ELECTRONIC RFP ANNOUNCEMENT, POTENTIAL OFFERORS WILL BE RESPONSIBLE FOR DOWNLOADING THEIR OWN COPY OF THE SOLICITATION AND AMENDMENTS. The Genetic Epidemiology Branch (GEB) of the National Cancer Institute is re-competing a contract for support for interdisciplinary studies, NO2-CP-60534, currently held by Westat, Inc. The contract will establish a mechanism to provide all the services required to conduct a wide variety of domestic and international family studies and field (case-control and cohort) studies. Although the scientific design and oversight of the activities are the responsibility of the Genetic Epidemiology Branch professional staff, the major activities of the contract provide: 1) nursing support including contacting family members, explaining the studies, enrolling family members, obtaining clinical information and records, requesting pathology slides for diagnosis confirmation, arranging for family members to be evaluated by GEB investigators in the Cancer Genetics Clinic at the Clinical Center, performing phlebotomy, obtaining other biologic specimens as necessary, arranging and conducting field trips to evaluate family members,verifying information for the family registry database, maintaining tracking systems for data and biologic specimens, developing and providing educational materials for participants, and participating in genetic counseling and risk notification; 2) maintenance of a locked medical record room to which GEB investigators have immediate access; 3) development of coordination and liaison at a local or international level with collaborating investigators or institutions whose cooperation is needed for the conduct of a study; 4) assistance in the design and pilot testing of forms required for field investigations (e.g., questionnaires, abstracting forms, coding forms, manuals for field procedures and other documents); 5) hiring, training and supervision of field personnel (interviewers, abstractors, and others); 6) identification of study subjects, including locating cancer patients and/or their relatives, selection of controls through such methods as random digit dialing and acquisition of appropriate study population rosters or files; 7) supervision and management of field operations; 8) collections of data (interviewing/record abstraction, biologic specimen collection and processing); 9) data reduction activities (coding, keying, and editing) of data collected into a format suitable for computer analysis; 10) quality control and standardization so that appropriate and valid data result. The maintenance of a secure record room which allows GEB investigators access to the medical records within 15 minutes is a mandatory requirement. There is also a mandatory requirement of the capability of nearly daily face to face meetings with the GEB staff. The anticipated solcitation issue date is approximately 21 days after publication of this notice, and proposals will be sue approximately 30 days after the issue date. The RFP may be accessed through the Acquisition Management Branch Home Page by using the following Internet address: http://amb.nci.nih.gov/rfp.htm. IT IS THE OFFERORS RESPONSIBILITY TO MONITOR THE ABOVE INTERNET SITE FOR THE RELEASE OF THE SOLICITATION AND ANY AMENDMENTS. All responsible sources may submit a proposal which shall be considered by the NCI. Point of Contact is Karen L. McFarlane; electronic mail address: km63k@nih.gov; fax 301-480-0241. No collect calls will be accepted. (0027) Posted 12/03/98 (W-SN276683). (0337)

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