National Institutes of Health, National Heart, Lung, and Blood Institute, Contracts Operations Branch, 6701 Rockledge Drive, Room 6100, MSC 7902, Bethesda, MD 20892

A -- IRON OVERLOAD AND HEREDITARY HEMOCHROMATOSIS STUDY -- COORDINATING CENTER SOL NHLBI-HC-99-03 DUE 031599 POC Lisa T. O'Neill, Contracting Officer, (301) 435-0345 WEB: Click here to download a copy of the RFP, http://www.nhlbi.nih.gov/nhlbi/rafs/rfas.htm. E-MAIL: Contracting Officer, lo17f@nih.gov. The National Heart, Lung, and Blood Institute is soliciting proposals for an epidemiologic study of the prevalence, genetic and environmental determinants, and potential clinical, personal, and societal impact of iron overload and hereditary hemochromatosis, in a multi-center, multiethnic, primary care-based sample of 100,000 adults. This information will be used to determine the feasibility and potential individual and public health benefits and risks of primary care-based screening and intervention for iron overload and hereditary hemochromatosis. The period of performance is for five years beginning on or about September 30, 1999. The study will consist of a Coordinating Center, 5-7 Field Centers and a Central Laboratory. This announcement invites all responsible sources interested in performing as the Coordinating Center for this study (RFP: NHLBI-HC-99-03) to submit a proposal which shall be considered by the agency. This is not the Request for Proposal (RFP); the Request for Proposal (RFP) must be downloaded from the NIH Web Site, which will be available on or about December 28, 1998, at the following Internet address: http://www.nhlbi.nih.gov/nhlbi/rafs/rfas.htm. The due date for proposal submission is March 15, 1999. Posted 12/10/98 (W-SN279134). (0344)

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