National Institutes of Health, National Institute of Allergy and Infectious Diseases, Contract Management Branch, Solar Bldg., Room 3C07, 6003 Executive Blvd. MSC 7610, Bethesda, MD 20892-7610

A -- COMPARATIVE EVALUATION OF CANDIDATE AIDS VACCINES IN RHESUS MACAQUES SOL NO1-AI-65303 POC Lawrence M Butler, Contracting Officer, (301) 496-0192 The National Institute of Allergy and Infectious Diseases (NIAID) intends to negotiate a modification to its 5 year cost-reimbursement contract with TSI Mason Laboratories, NO1-AI-65303, as a sole source under authority of 41 USC 253 (c) (1) and FAR 6.302-1. The contract currently conducts evaluations of candidate AIDS vaccines in non-human primates, including selected immunological evaluations during immunization and quantitative determination of virus load after challenge. The negotiated modification will expand the capacity of the contract to make it possible to conduct a comparative trial of five candidate vaccines. An additional 150 rhesus macaques will be individually housed under biocontainment conditions appropriate for SIV (BSL 2-3) for the estimated two year duration of the study. See Numbered Note 22. No collect calls will be accepted. Posted 12/18/98 (W-SN281755). (0352)

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