U.S. Environmental Protection Agency, Program Contract Service Center (3803R), 401 M Street, SW, Washington, DC 20460-0001

B -- STUDY OF EXPOSURE TO CHILDREN FROM DRINKING WATER USING (NHEXAS) DATA SOL DDE406 DUE 020399 POC Mark Heare WEB: NOT AVAILABLE, NOT AVAILABLE. E-MAIL: NOT AVAILABLE, HEARE.MARK@EPAMAIL.EPA.GOV. The U.S. Environmental Protection Agency (EPA) is issuing an intent to award for services to which the Government intends to award a firm fixed price contract using the Simplified Acquisition Procedures of FAR Part 13 to: Dr. Timothy Buckley; John Hopkins Universidy School of Heigene and Public Health; 615 N. Wolfe Street, Baltimore, MD 21205. The EPA is FACNET certified. NO PHONE CALLS ACCEPTED. Two copies of all proposals, for the following statement of work, should be delivered to the following address, (fax/e-mail copies will not be accepted): US EPA; 401 M Street, SW; Mail Code 3803R; Washington, DC 20460 Attn: Mark Heare -- HANDCARRY TO: 1300 Pennsylvania Avenue, NW; Bid and Proposal Room -- 6th floor; Washington, DC 20003; Attn: Mark Heare -- Due Date: 2/3/99; 2:30pm EST (Any proposal received after the due date will not be considered or opened.) Quotes are due in writing no later than 15 days of notice of this solicitation. This is a combination synopsis/solicitation for these services and will be the only solicitation to be issued. Any contractor/vendor able to meet the requirements must demonstrate in writing by the closing date. All responsible sources solicitated my submit a bid, proposal, or quotation, that shall be considered. STATEMENT OF WORK FOR NHEXAS ANALYSIS OF DRINKING WATER -- BACKGROUND: The Safe Drinking Water Act (SDWA) as amended by Congress in 1996 requires EPA to promulgate national drinking water regulations for contaminants and disinfectant byproducts. The SDWA requires EPA to use sound science to assure the protection of human health and to consider the effects of drinking water contaminants in sensitive subpopulations (e.g., children, pregnant women, the elderly, different ethic groups, etc) in setting safety standards. Accurately characterizing the human exposure to drinking water contaminants and disinfection byproducts is critical in meeting the goals of the 1996 SDWA. This research effort will test if NHEXAS drinking water data can be used to improve exposure estimates and help OW meet these goals. SCOPE OF WORK: The contractor shall compile the NHEXAS data into a SAS database. The contractor shall group these data according to OW criteria for drinking water source, age classification, subpopulation characteristics, geographic locality, and socioeconomic demographics. The contractor shall analyze these data to estimate chemical exposures from drinking water and other sources in these various groups. This includes analysis of individual media to determine the amount of exposure attributable to these sources and to multimedia analyses to estimate the aggregate exposure. The contractor shall construct distributions of chemical exposures for analysis. The contractor shall analyze the results of individuals in the 90th percentile group to determine if they display any common characteristics. DELIVERABLES: Milestone Task Submission Date* 1 Rank chemicals measured in NHEXAS with OW 3 months 2 Identify issues and develop hypotheses 3 months 3 Obtain OW criteria forexposure and risk assessment 3 months 4 Compile NHEXAS drinking water data into SAS data base 6 months 5 Analyze, summarize NHEXAS drinking water data 9 months 6 Construct exposure assessments 9 months 7 Compare NHEXAS results to OW exposure factors 9 months 8 Construct risk assessments 9 months 9 Produce NHEXAS data base and report for OW 12 months 10 Submit journal article on results for publication 12 months * post award Posted 01/12/99 (W-SN287283). (0012)

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