National Institutes of Health, Division of Research Contracts, OCM/OA/OD, 6100 Executive Blvd., MSC 7540, Room 6E01, Bethesda, Maryland 20892-7540

A -- INVESTIGATIONAL NEW DRUG TOXICOLOGY FOR DRUGS TO TREAT ALZHEIMER'S DISEASE AND OTHER AGING-RELATED DISEASES SOL NIH-AG-99-03 DUE 020599 POC Teresa A. Baughman, Contracting Officer, 301-496-4487 WEB: Click here to download a copy of the Statement of Work, http://ocm.od.nih.gov/drc/rfp.htm. E-MAIL: Click here to contact the Contracting Officer via, tb14j@nih.gov. The National Institute on Aging (NIA), National Institutes of Health (NIH) is seeking small businesses with the capabilities to evaluate acute and chronic toxicity in rodents and dogs of drugs which are proposed to have potential use in the treatment of Alzheimer's disease and other aging-related diseases. The data generated from these studies will be used as part of the filing of an Investigational New Drug Application to the Food and Drug Administration in order to receive approval to use the drugs in humans. The work to be performed includes toxicity evaluations using fully audited Good Laboratory Practices (GLP) dose range finding studies, GLP 13 week subchronic oral toxicity studies in rats or beagle dogs, and other ancillary studies. The full Statement of Work and Technical Evaluation Criteria for this project are located at the following website: http://ocm.od.nih.gov/drc/rfp.htm THIS IS NOT A REQUEST FOR PROPOSALS (RFP)and does not commit the Government to award a contract now or in the future.No RFP is available at this time. Small business concerns that believe they possess the capability necessary to undertake the work described at the above referenced website should submit an original and two (2) copies of their capability statement by February 5, 1999. The Standard Industrial Classification (SIC) code is 8731. SEE NUMBERED Note 26. No collect calls will be accepted.**** Posted 01/19/99 (W-SN288944). (0019)

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