National Institutes of Health, National Institute of Allergy and Infectious Diseases, Contract Management Branch, Solar Bldg., Room 3C07, 6003 Executive Blvd. MSC 7610, Bethesda, MD 20892-7610

A -- RESEARCH RESOURCE FOR GENETICS OF FAMILIES WITH MULTIPLE AUTOIMMUNE DISEASES SOL RFP-NIH-NIAID-DAIT-99-32 DUE 043099 POC Mr. Bruce E. Anderson, Contracting Officer, EMail: ba9i@nih.gov, Telephone: 301-496-8371, FAX: 301-402-0972 The Division of Allergy, Immunology and Transplantation of the National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), has a requirement to establish the Research Resource for Genetics of Families with Multiple Autoimmune Diseases, a core facility dedicated to the collection and characterization of multiplex (2 or more affected individuals) families affected by two or more autoimmune diseases. The facility will operate two simultaneous activities. It will serve as a registry for pedigrees of such families by collecting, validating, and updating clinical, demographic, and laboratory data on multiplex families affected by two or more autoimmune diseases. The facility will also operate a repository of immortalized cells and DNA samples obtained from enrolled family members. The contents of the database, cells, and DNA samples will be made available to basic and clinical researchers. The facility will also maintain a database of published genotypic data on these families. The NIAID expects that the availability of these resources will encourage and accelerate research on genes, which confer susceptibility and/or resistance to the development of autoimmune diseases. The use of unified criteria for enrollment and processing of cell and DNA samples will simplify the comparison of experimental data obtained by different laboratories without jeopardizing the individual research projects. RFP NIH-NIAID-DAIT-99-32 will be available electronically on or about February 8, 1999 and may be accessed through the NIAID Contract Management Branch (CMB) Homepage, by the following electronic address and instructions: Access by http://www.niaid.nih.gov/contract, and select the "RFPs" link and then select "RFP-NIH-NIAID-DAIT-99-32". Please note that the RFP for this acquisition has been revised to include only the Statement of Work, deliverable and reporting requirements, special requirements and mandatory qualifications, if any, the Technical Evaluation Criteria, and the proposal preparation instructions. All information required for the submission of an offer will be contained in the electronic RFP package. Following proposal submission and review, offerors may be requested to provide additional documentation to the Contracting Officer. Proposals in response to this RFP will be due on or about April 30, 1999. Any responsible offeror may submit a proposal, which will be considered by the Government. It is anticipated that a single cost-reimbursement contract will be awarded for a maximum period of five (5) years. Subcontracting is permitted as noted in the Statement of Work. This advertisement does not commit the Government to award a contract. No collect calls will be accepted. The Division of Allergy, Immunology and Transplantation of the National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), has a requirement to establish the Research Resource for Genetics of Families with Multiple Autoimmune Diseases, a core facility dedicated to the collection and characterization of multiplex (2 or more affected individuals) families affected by two or more autoimmune diseases. The facility will operate two simultaneous activities. It will serve as a registry for pedigrees of such families by collecting, validating, and updating clinical, demographic, and laboratory data on multiplex families affected by two or more autoimmune diseases. The facility will also operate a repository of immortalized cells and DNA samples obtained from enrolled family members. The contents of the database, cells, and DNA samples will be made available to basic and clinical researchers. The facility will also maintain a database of published genotypic data on these families. The NIAID expects that the availability of these resources will encourage and accelerate research on genes, which confer susceptibility and/or resistance to the development of autoimmune diseases. The use of unified criteria for enrollment and processing of cell and DNA samples will simplify the comparison of experimental data obtained by different laboratories without jeopardizing the individual research projects. RFP NIH-NIAID-DAIT-99-32 will be available electronically on or about February 8, 1999 and may be accessed through the NIAID Contract Management Branch (CMB) Homepage, by the following electronic address and instructions: Access by http://www.niaid.nih.gov/contract, and select the "RFPs" link and then select "RFP-NIH-NIAID-DAIT-99-32". Please note that the RFP for this acquisition has been revised to include only the Statement of Work, deliverable and reporting requirements, special requirements and mandatory qualifications, if any, the Technical Evaluation Criteria, and the proposal preparation instructions. All information required for the submission of an offer will be contained in the electronic RFP package. Following proposal submission and review, offerors may be requested to provide additional documentation to the Contracting Officer. Proposals in response to this RFP will be due on or about April 30, 1999. Any responsible offeror may submit a proposal, which will be considered by the Government. It is anticipated that a single cost-reimbursement contract will be awarded for a maximum period of five (5) years. Subcontracting is permitted as noted in the Statement of Work. This advertisement does not commit the Government to award a contract. No collect calls will be accepted. Posted 01/20/99 (W-SN289797). (0020)

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