National Cancer Institute, Research Contracts Branch, PCPSS, Executive Plaza South, Room 635, Bethesda, Md 20892

A -- EFFICACY STUDIES OF CHEMOPREVENTIVE AGENTS IN ANIMAL MODELS SOL MAA-RFP-NCI-CN-95024-72 DUE 040199 POC Jacqueline Ballard, Contracting Officer, 301-435-3795 WEB: http//www.amb.nci.nih.gov/rfp.htm1, http//www.amb.nci.nih.gov/rfp.htm1. E-MAIL: ballardj@mail.nih.gov, ballardj@mail.nih.gov. SEMI-ANNUAL MASTER AGREEMENT ANNOUNCEMENT RFP NC1-CN-95024-72 "Efficacy Studies of Chemopreventive Agents in Animal Models (Original RFP NC1-CN-85051-72)" RFP Issue : OPEN (ELECTRONIC RFP ANNOUNCEMENT: POTENTIAL OFFERORS WILL BE RESPONSIBLE FOR DOWNLOADING THEIR OWN COPY OF THE SOLICITATION AND AMENDMENTS.) Proposals Due : APRIL 1, 1999 The Division of Cancer Prevention (DCP), National Cancer Institute (NCI), National Institutes of Health (NIH), intends to expand the existing Master Agreement (MA) pool for "Efficacy Studies of Chemopreventive Agents in Animal Models". ALL MA HOLDERS ALREADY IN THE EXISTING MA POOL NEED NOT RESPOND TO THIS ANNOUNCEMENT. Offerors selected for award of a MA may be solicited to provide the adequate capability and technical expertise to furnish all necessary services, qualified personnel, materials, supplies and facilities to carry out the order issued. Offerors should be capable of performing animal cancer model studies to evaluate the efficacy of various designated chemopreventive agents at several dose levels of models for chemopreventive studies. This work to be performed shall identify initial leads on designated agents and expand the data base range of species. Individual work requirements (Master Agreement Orders (MAOs) ) will be issued during the period of performance and awarded based upon competition among members of the MA Pool. The MA mechanism is a pre qualification process to enable qualified sources to compete for and perform future contracts which will be awarded based on Request for Proposals (RFPs). The MA award is non-monetary and is exclusively for the purpose of compiling a pool of contractors who are pre-qualified to perform services for efficacy studies. The obligation of funds shall be accomplished solely through the award of contracts (MAO). Any MA awarded as a result of this solicitation will be in effect from the effective date to December 31, 2002. This solicitation will be open for the duration of the existing MA Pool with due dates for receipt for proposals semi-annually, April 1 and November 1 (or the next business day) of each year. All responsible sources meeting these criteria are encouraged to submit a proposal and a sample requirement to be considered by the NCI. The RFP may be accessed through the Research Contracts and Acquisition Branch Home Page by using the following Internet address: http://amb.nci.nih.gov/rfp.htm. It is the offeror's responsibility to monitor the above internet site for the release of this solicitation and amendments, if any. POTENTIAL OFFERORS WILL BE RESPONSIBLE FOR DOWNLOADING THEIR OWN COPY OF THE SOLICITATION AND AMENDMENTS. (Hard copies will be available only upon individual request). Point of contact: Jacqueline Ballard, Contracting Officer, NCI, RCAB, PCPSS; 6120 Executive Boulevard, Executive Plaza S., Room 635F, Rockville, MD. 20852; Email address: ballardj@mail.nih.gov.; Fax 301-402-8597. No collect calls will be accepted. Posted 02/03/99 (W-SN294025). (0034)

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