Centers for Disease Control and Prevention (CDC), Procurement & Grants Office, Contract Management Branch, 255 East Paces Ferry Rd, NE, Rm 500, Atlanta, GA 30305

A -- TUBERCULOSIS TRIALS CONSORTIUM (TBTC) SOL 1999N00083 POC Sherry Smallwood, Contract Specialist, (404) 842-6791 The Centers for Disease Control and Prevention (CDC) intends to award a multiple-award contract for the conduct of clinical research in the areas of diagnosis and treatment of latent and active tuberculosis (TB). Each contractor shall conduct all phases (enrollment, treatment, and follow-up) of clinical trials in patients with latent TB infection and active TB disease. The scope of activities will range from small studies requiring moderate laboratory support, to large, long-term trials to evaluate clinical therapies and management strategies. The contractors shall furnish all labor, materials, facilities, and equipment necessary to concurrently perform multiple studies, using procedures outlined in each study's applicable protocol. These studies will follow the procedures detailed in their applicable protocols with regard to scheduled clinic visits, required laboratory tests (performed in qualified laboratories), required chest x-rays, and appropriate data collection forms to be used for reporting results. The contractors shall provide qualified medical staff with expertise in conducting clinical trials for the treatment of active TB, for the prevention of active TB in patients with latent TB infection, and for the evaluation of new tests or approaches for the diagnosis of TB infection and disease. Each contractor shall enroll a minimum of 15 newly diagnosed active TB patients each year, and a minimum of 25 patients with latent TB infection each year. Each contractor shall also participate fully as a member of the investigator-driven TB Trials Consortium (TBTC), whose By-Laws are available with the solicitation. The awarded contracts shall be of 10 years duration, performed in ten annual phases of 12 months each. Only written requests for copies of the solicitation will be honored. On February 18, 1999, the CDC's Procurement and Grants offices will begin moving from our current location at 255 East Paces Ferry Road, N.E., Room No. 500, Atlanta, Georgia 30305, to a different facility in the Atlanta area. All written requests for the solicitation mailed for CDC's receipt on or before February 18, 1999, should be mailed to: Centers for Disease Control and Prevention, Contracts Management Branch, PGO, Attn: Sherry Smallwood, 255 East Paces Ferry Road, N.E., Room No. 500, Atlanta, GA 30305. Written requests mailed for CDC's receipt after February 18, 1999, must be mailed to the new address: Centers for Disease Control & Prevention, Contracts Management Branch, PGO, Attn: Sherry Smallwood, 2920 Brandywine Road, Room 3208, Atlanta, GA 30341-4146. Written requests may be faxed to the Contract Specialist to the following numbers: 404-842-6727 for receipt on or before February 17, 1999, or 770-488-2667 for receipt on or after February 22, 1999. Written requests may also be E-Mailed to the Contract Specialist at SVS9@CDC.GOV. Telephone requests will not be accepted. The date specified for receipt of offers will be approximately 40 days after the solicitation issue date. The solicitation issue date will be on or about February 25, 1999. Posted 02/05/99 (I-SN295712). (0036)

Loren Data Corp. http://www.ld.com (SYN# 0001 19990209\A-0001.SOL)