Acquisitions Management Operations Branch, NIAID, 6003 Executive Blvd, Solar Building, Room 1C38, Contracts Section, Bethesda, MD 20892-7605

R -- OPERATION AND MAINTENANCE OF A CHIMPANZEE BREEDING COLONY POC Karin E. Edd y, Contracting Officer / Ivan Hernandez, Contract Specialist, 301-496-3878 The National Institute of Allergy and Infectious Diseases, Division of Intramural Research, seeks Capability Statements from qualified sources for the purpose of providing on loan to the NIAID approximately 10 hepatitis and respiratory syncytial virus free infant chimpanzees (Pan troglodytes) annually for hepatitis, respiratory virus, and other infectious disease research and vaccine development. It is expected that the operation of a chimpanzee breeding colony will be necessary for this provision of infant chimpanzees. Any Offeror shall possess, or be able to acquire, all necessary personnel, housing, facilities, and equipment to adequately care for the breeding chimpanzees and progeny. The animal facilities provided must be of such design to insure isolation from other animals known or suspected to be infected with any hepatitis virus or other infectious agent or any other common primate infection such as tuberculosis. Upon termination of studies utilizing chimpanzees, the Government will return sameto Any Offeror. Any Offeror will be responsible for the health and daily care of these chimpanzees for the remainder of the chimpanzee's life. Any Offeror should have the capability to isolate or appropriately separate most returned chimpanzees from the rest of their colony since many animals will have been exposed to hepatitis C virus. The Government shall establish a one time loan fee schedule for the Government's use of the chimpanzees, and a return fee schedule for the endowment that will be paid to Any Offeror depending on the age and use history of the chimpanzee being returned. Any Offeror will be free to seek additional sources of income or support for the chimpanzees once they are returned to their facility by the NIAID. Any Offeror must have an Office for Protection from Research Risks Assurance Number and a United States Department of Agriculture R Registration. Any Offeror must have or be able to obtain a Association for Assessment and Accreditation of Laboratory Animal Care International file number. The facility in which the animals are housed shall be operated in compliance with: a. The Animal Welfare Act (P.L. 89-544, as amended) Rules and Regulations published in the Code of Federal Regulations (CFR), Title 9 (Animals and Animal Products), Chapter 1, Subchapter A (Animal Welfare), Parts 1, 2, and 3. b. Public Health Service (PHS) Policy on Humane Care and Use of Laboratory Animals, updated 1996. c. The Guide for the Care and Use of Laboratory Animals, revised 1996. d. Biosafety in Microbiological and Biomedical Laboratories (CDC-NIH 1993). e. Occupational Health and Safety in the Care and Use of Research Animals (NRC 1997). Any Offeror must be able to document the experience and capabilities of professional and technical personnel assigned to this project for providing animal care. The professional and technical personnel shall have extensive experience in non-human primate medicine and surgery and infectious disease research. The professional staff will also be evaluated with respect to specialty board certification by the American College of Laboratory Animal Medicine, advanced degrees, and residency training in laboratory animal medicine. The technical staff will also be evaluated with respect to American Association for Laboratory Animal Science technician certification. Capability statement may be submitted to the above addess. ***** Posted 04/15/99 (W-SN320698). (0105)

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