National Institutes of Environmental Health Sciences, Research Contracts Branch, DERT, P.O. Box 12874, Building 4401, Research Commons, 79 T.W. Alexander Drive, Research Triangle Park, NC 27709

A -- RODENT DISEASE DIAGNOSTIC LABORATORY" SOL NIH-ES-99-32 DUE 062599 POC Vondia C. Malone, Contract Specialist, (919) 541-0428,e-mail MaloneV@niehs.nih.gov, and FAX (919) 541-2712 WEB: None, None. E-MAIL: None, None. The National Institute of Environmental Health Sciences (NIEHS)is soliciting proposals from offerors having the capability to establish, operate and maintain diagnostic laboratory to provide Rodent Disease Diagnostic Laboratory support for monitoring the microbial and health status of the breeders and weanlings of the NIEHS/National Toxicology Program (NTP) rodent production colonies and the animals on test in toxicology testing laboratories. To accomplish these objectives, timely and accurate performance of a large battery of diagnostic procedures to determine microbial and parasitic status, and pathologic changes on each animal submitted: viral and mycoplasmal serology profiles on each serum submitted will be necessary along with expeditious reporting of all data to the Project Officer. The Offeror shall have the capabilities to detect the following agents: Viruses, mycoplasma, bacteria, protozoa, mycotic organisms, helminth parasites and ectoparasites. Additional investigations such as diagnosis of disease outbreaks in the production colonies and the testing laboratories shall be similarly undertaken as needed and in accordance with the general goal of eliminating all spontaneous diseases. Specifically, the Offeror shall routinely monitor approximately 40 mice and 20 rats per month for a total of 720 animals/year, for infectious agents and spontaneous disease processes. The Offeror shall perform viral and mycoplsmal serology profiles on approximately 600 rat and 800 mouse serum samples per year by accurate, reproducible and sensitive methods available. The period of performance will be eight years. The proposed contract listed here is 100% small business set-aside. Request must reference RFP No. NIH-ES-99-32 and must be directed to the office listed above. See Numbered Notes 1 and 26.***** Posted 04/23/99 (W-SN323825). (0113)

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