NCI Frederick Cancer Research and Development Center (NCI-FCRDC), P.O. Box B, Frederick, Maryland 21702-1201

R -- HOUSING CONVENTIONAL ANIMALS SOL F99-1 DUE 060899 POC Point of Contact -- Joanne Clarence, Contracts Specialist, 301-846-1721, Contracting Officer -- Dennis J. Dougherty, 301-846-1087 E-MAIL: Joanne Clarence, Contracts Specialist, jclarence@mail.ncifcrf.gov. Science Applications International Corporation (SAIC)-Frederick is soliciting proposals from qualified firms to house "conventional" rodents (mice, rats, hamsters and guinea pigs) and rabbits. The facility must be AAALAC accredited and located within a forty (40) mile radius of Frederick, Maryland. Services to be provided include animal care, related technical support and transportation of material to and from either the National Institutes of Health (NIH) in Bethesda, Maryland or the National Cancer Institute (NCI) Frederick Cancer Research & Development Center (FCRDC) in Frederick, Maryland. Related technical support includes the capability to perform, at a minimum, the following services: (1)routine injection, tumor palpation, necropsy, minor surgery; (2) breeding to include backcrossing, background changing and maintenance of all necessary records; (3) tail snips and DNA preparation for PCR testing; (4) monoclonal antibody production; (5) polyclonal antibody production; (6) timed meetings for rederivation (embryo transfer and hysterectomy rederivation) and (7) antibody profile testing. In addition, a computer based record keeping system with the capability to send and receive data between the subcontractor and investigators at both NIH and NCI-FCRDC should be available. The animals to be housed may be infected with any or all of the following agents: (1) Mice: Sendai Virus, Parvovirus, Mouse Hepatitis Virus, Pinworms -- S. obvelata, A. teraptera and Ectoparasites; (2) Rats: Sendai Virus, PVM, RCV/SDA, KRV/H-1 and Pinworms -- S. muris; and (3) Hamsters: Protozoa -- Trichomonads, spironucleus, Girardia. Dpending upon scientific need, animals to be housed under this contract may have been infected by other agents in addition to those listed above. However, none of the animals to be housed under this agreement will knowingly be infected with Lymphocytic Choriomeningitis Virus, Ectromelia or Salmonella sp. It may be necessary to accept animals with less than twenty-four (24) hour notice. Offerors shall possess the ability to provide consulting services to the investigators from a Veterinarian, an Animal Geneticist, a Board Certified Animal Pathologist or similar professionals. The subcontractor will be responsible for the disposal of chemical and special medical wastes and must provide a Chemical Hygience Officer, Chemical Hygiene Plan, etc., as described in 29 CFR 191.1450. Material safety data sheets, records and other related information will be maintained at the subcontractor's site. Spill response and clean up will be the subcontractor's responsibility. The contract will be in effect for a period of one (1) year and may be extended by SAIC for two (2) one- year periods. The total maximum period, including the two (2) one-year renewal periods, will not exceed three (3) years. Evaluation factors for selection will be based on the firm's past performance (10%), animal care capabilities (30%), technical support capabilities (30%) and cost (30%). Request For Proposals (RFP) will be available upon request. Telephone calls for solicitations will be accepted. SAIC intends to evaluate proposals and make an award without discussions. Offerors should provide their best offer initially from a cost & technical standpoint. Each offeror will be required to submit both a technical & cost proposal based upon the evaluation factors identified in the RFP. Proposals must be received on or before June 8, 1999, 4:00 pm, eastern standard time, at the following address: SAIC-Frederick, NCI-Frederick Cancer Research & Development Center, Bldg 244, Miller Drive, Frederick, MD 21702-1201, Attn: Joanne Clarence. Submittals received after the due date will be returned without consideration. Award of a single requirements contract will be made to the "best value" offeror by approximately July, 1999. This announcement supersedes all previous announcements for these services. Posted 05/06/99 (W-SN328580). (0126)

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