National Institutes of Health, Division of Research Contracts, OCM/OA/OD, 6100 Executive Blvd., MSC 7540, Room 6E01, Bethesda, Maryland 20892-7540

A -- PATHOLOGY MONITORING OF NIA AGED RODENT COLONIES SOL NIH-AG-99-11 DUE 052799 POC Jonathan Ferguson, Contract Specialist, (301) 496-4487 E-MAIL: click here to contact the Contract Specialist via, jf27t@nih.gov. The National Institutes of Health is seeking small businesses who can perform clinical evaluation of mice and rats as described below. Upon responding, identify whether your organization has catalog prices for the tests described in the Basic and Comprehensive Profiles. Specifically, the contractor shall: i) Describe general conditions of all animals, weight, and any visible lesions or symptomology; and ii) Conduct a gross pathology on all animals using procedures that will maximize the chance for detection of the agents listed below. All tests are applied to both rats and mice unless indicated specific to either rats (R) or mice (M). BASIC PROFILE: Viruses- MHV (M), Ectromelia virus (M), Mouse parvovirus(es) (M), Theiler's (M), PVM, LCMV (M), Rotavirus (M), Sendai, Rat Parvoviruses (R), Rat coronovirus (R); Bacteria -- Mycoplasma pulmonis, Corynebacterium kutscheri, Strep, pneumoniae, Citrobacter freundii (4280), Pseudomonas sp., Salmonella enteritidis; Parasites: Spironucleus muris, Giardia sp., Cryptosporidium sp., Syphacia sp., Hymenolepis sp., Mites; Histopathology: Liver, GI tract- Small intestine, Cecum, Colon -- Respiratory tract- Nasal passages, Middle ears, Lungs, Trachea. COMPREHENSIVE PROFILE: Viruses- Reovirus(es), Polyomavirus (M), Adenoviruses, LDV (M), TMEV (R), Hantavirus (R); Bacteria- CAR bacillus (histopathology), Pasteurella pneumotropica, Bacillus piliformis (histopathology); Histopathology: Brain, Skin, Salivary gland (R), Harderian gland (R), Spleen, Thymus, Heart, Kidney, Reproductive organs-Ovaries, Uterus, Testes, Prepuce. Responses to this CBD announcement should be submitted in writing to the Contract Specialist by 4:00 p.m. local time on May 27, 1999. Posted 05/12/99 (W-SN330817). (0132)

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