National Institutes of Health, Office of Procurement Management, 6011 Executive Blvd., Rockville, Maryland 20892-7260

R -- STUDY (DETERMINE THE HERITABILITY OF PMS IN FEMALE TWINS) SOL 263-99-P-(AB)-0038 DUE 070699 POC Ann Bryant, Contract Specialist, 301/402-3080 The National Institutes of Health, National Institute of Mental Health, Bethesda, Md., intends to negotiate with Research Data, Inc., 900 W. Leigh St., Richmond, Va. 23220, the only known source, under the authority of FAR 6.302-1 for this particular study. The purpose of the study is to determine the heritability of Premenstrual Syndrome (PMS) in female twins sharing the same genes (monozygotic) compared with twins sharing only 50% of their genes (dizygotic). The Contractor shall provide the following: 1) A Registry of at least 1,500 well characterized female twin pairs to be used as subjects of the proposed study; 2) Utilize an expert in the field of Psychiatric Genetics to Analyze the data that would be obtained in this enterprise; 3) Develop questionnaires, which shall include printing and distribution; 4) Data entry, imaging, storage and analysis; set-up costs; and follow-up phone interviews; and 5) Acquire DNA samples and provide processing and analysis of the samples. The performance period shall be for a twelve month period, with three (3) additional twelve month option periods. The study is divided into three (3) phases: 1) Phase I -- provide questionnaire development, printing, distribution and recording; 2) Phase II -- provide instrument development, printing distribution and retrieval; and 3) Phase III -- Provide blood sampling and analysis. The Government reserves the right to exercise the options. Depending on the results retrieved from Phase II, the Government will determine the feasibility of continuing with Phase III. This is not a formal solicitation. However, firms responding to this notice must furnish concise responses directed specifically to the requirements mentioned above. Sources demonstrating the capability to accomplish the above shall supply pertinent information in sufficient detail to demonstrate their ability to perform. Information furnished should include enough material to perform a proper evaluation. Award will be made to the technically acceptable low offer. Responses will not be considered as either bids or proposals, cost or pricing data must not to be submitted. Interested parties may submit adequate detailed data by which to evaluate capabilities. Send original and two copies of responses to the attention of Ann Bryant at the address above. This notice may represent the only official notice of such procurement. Closing date for receipt of responses is forty-five (45) calendar days from the publication date of this notice. FAX responses are acceptable at 301/402-3406. See numbered Note 22. Posted 05/20/99 (W-SN333888). (0140)

Loren Data Corp. http://www.ld.com (SYN# 0065 19990524\R-0002.SOL)