DHHS/PHS/FDA/Office Of Facilities, Acquisition, And Central Services, Division of Contracts and Program Management, HFA-512(COB), 5600 Fishers Lane, Rockville, MD 20857

B -- PILOT STUDY TO ASSESS THE POSSIBLE ROLE OF IMMUNOLOGIC FACTORS SOL A157446 DUE 062199 POC Dee Gibson, Contract Administrator, (301) 827-7177 The Food and Drug Administration (FDA) intends to award a purchase order on or about June 21, 1999 to Johns Hopkins University's Center for Vaccine Safety (CVS), on a sole-source basis to provide research in a pilot study to access the possible role of immunologic factors in persons who develop multiple sclerosis after hepatitis B vaccine. The task involved will be: the recruitment of subjects and data collection and a laboratory analysis to determine the reactivity of the subjects' T-cells to Myelin Basic Protein and Hepatitis B vaccine antigens will be developed and conducted on 30 subjects in a blinded fashion. Authority for this non-competitive acquisition is found at FAR 13.106-2(a) (5). This notice is not a request for quotations; however, interested parties may identify their interest and capability to satisfy the Governments requirement no later than the response date the response date. Capability statements must include documentation of an in-depth knowledge and prior experience of this type of work. A determination by the Government not to compete this proposed purchase order based upon responses to this notice is solely within the discretion of the contracting officer. A solicitation document is not available. Posted 06/04/99 (W-SN339496). (0155)

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