National Institutes of Health, National Institute of Allergy and Infectious Diseases, Contract Management Branch, Room 2230, 6700-B Rockledge Drive, MSC 7612, Bethesda, MD 20892-7612

A -- CHEMISTRY AND PHARMACEUTICAL RESOURCES FOR THERAPEUTICS DEVELOPMENT: DEVELOPMENT AND MANUFACTURE OF DOSAGE FORMS SOL NIH-NIAID-DAIDS-00-11 DUE 110199 POC Grace A. Bruce, Contract Specialist, 301-496-0195/Paul D. McFarlane, Contracting Officer, 301-496-0349 The Drug Development and Clinical Sciences Branch, Therapeutics Research Program, Division of AIDS, National Institute of Allergy and Infectious Diseases (NIAID), NIH, has a requirement to develop and manufacture clinical dosage forms for drugs intended for use in animal efficacy models, preclinical toxicology studies, and clinical trials. These efforts will support a comprehensive portfolio of contract resources to discover and develop novel therapeutic agents for the prevention and treatment of infections caused by human immunodeficiency virus, AIDS-associated opportunistic pathogens, and other infectious agents. This contract will help assure that experimental therapies will be appropriately formulated for animal and human studies and that the final manufactured dosage forms conform to applicable FDA regulatory requirements. It is anticipated that one (1) cost reimbursement, completion type contract will be awarded for a period of five (5) years, beginning approximately June 1, 2000. RFP NIH-NIAID-DAIDS-00-11 will be available electronically on or about August 16, 1999, and may be accessed through the NIAID Contract Management Branch (CMB) Home Page by using the following electronic address and instructions: NIAID/CMB Home Page (via the WWW): Use http://www.niaid.nih.gov/contract to access the NIAID/CMB Home Page. Once at the NIAID/CMB Home Page, click on the "RFPs" link and then click on "RFP NIH-NIAID-DAIDS-00-11." Please note that the RFP for this acquisition has been revised to include only the Work Statement, Deliverable and Reporting Requirements, Special Requirements and Mandatory Qualification, if any, the Technical Evaluation Criteria, and the Specific RFP Instructions and Provisions. All information required for the submission of an offer will be contained in the electronic RFP package. Following proposal submission and the initial review process, Offerors comprising the competitive range will be requested to provide additional documentation to the Contracting Officer. Responses to this RFP will be due on or about November 1, 1999. Any responsible Offeror may submit a proposal, which will be considered by the Government. This advertisement does not commit the Government to award a contract. Point of Contact: Grace A. Bruce, Contract Specialist Electronic mail address: gb15w@nih.gov Telephone: (301) 496-0195 FAX: (301) 480-5253 No collect calls will be accepted. Posted 08/04/99 (W-SN363255). (0216)

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