National Cancer Institute, Research Contracts Branch, PSAS, 6120 Executive Blvd, EPS/Room 638, Bethesda, MD 20892-7227

R -- PROFESIONAL, ADMINSISTRATIVE, AND MANAGEMENT SUPPORT SERVICES. SOL RFQ-NCI-90160 DUE 081699 POC Cynthia Brown, Purchasing Agent, 301-402-4509, Todd Cole Contracting Officer The National Institutes of Health, National Cancer Institute(NCI),plans to procure services from The Health Research Association(HRA), University of Southern California(USC), 1640 Maengo S., Los Angeles, CA 90033 to measure hormones in tissue and serum samples collected in an NCI methodologic study. The purpose of the methodologic study is to investigate whether serum levels of hormone reflect intraprostatic androgenicity and to provide information to aid the future direction of epidemiologic studies on hormones and prostate cancer. NCI has collected 1,080 prostatic tissue samples and 100 serum samples and the purpose of this acquisition is to determine the levels of testosterone (T), dihydrotestosterone (DHT), DHT sulfate,androstanediol glucuronide, estradiol, estrone, estrone sulfate, and sex hormone binding globulin (SHBG). HRA has measured serum and tissue hormones in the past using specific assays and the data from that study, which is similar to this one, will be compared with the newdata. In addition, a limited amount of tissue samples are available for each study subject. Dr. Frank Stanczyk, HRA, USC, has developed special assays to measure all seven hormones at the same time on very small samples and has demonstrated their use. His facility is the only one known to NCI that can perform all the assays at the same time using very small samples. This is not a request for competitive proposals. However, interested parties who believe they have this capability and can meet NCI's requirements may submit a capability statement for evaluation. The statment must be in writing and must contain material in sufficient detail to allow NCI to determine if the party can meet the requirement. Capability statements must be received in the contractng office by 3:00 p.m. EST, on August 16, 1999. For further information please contact Cynthia Brown, (301) 402-4509. A determination by the Government not to compete this proposed requirement based upon response to this notice is solely within the discretionof the Government. Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement. Please reference RFQ-NCI-90160. No collects calls will be accepted. Posted 08/05/99 (W-SN363723). (0217)

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