U.S. Environmental Protection Agency, 75 Hawthorne St. PMD-8, San Francisco, CA 94105-3901

B -- DUST SAMPLE ANALYSIS SOL PR-CA-99-00305 DUE 091099 POC Alvin Wong, (415) 744-1023 FAX: (415) 744-1680 WEB: none, none. E-MAIL: none, wong.alvin@epa.gov. STATEMENT OF WORK TITLE: Analytical Support for In-vehicle Pesticide Dust Monitoring I. WORK ASSIGNMENT MANAGER (WAM) Raymond Chavira USEPA Region 9 Pesticides Program 75 Hawthorne St., CMD-4-3 San Francisco, CA 94510-3901 II. BACKGROUND USEPA is committed to protecting the health of agricultural workers by insuring that sound evaluations and practices are used for risk assessments conducted in support of the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA). Passage of the Food Quality Protection Act (FQPA) has led the Agency to consider childhood pesticide exposure in aggregate and to develop procedures for assessing risks from "non-occupational" pesticide exposure. Few studies to date have evaluated exposures in potential high risk populations such as children living with farmers, farmworkers, or near a farm. In addition, Executive Order 13054 (April 21, 1997) requires the Agency to identify and assess environmental risks that may disproportionately affect children and to ensure the Agency's activities address children's environmental health risks. Quantitative examination of major pathways and routes of exposure to pesticides is essential for determining human risk, especially to those individuals residing and working in agriculturally intensive areas. It has been established that semi-volatile pesticide residues accumulate indoors (Davies et al. (1993); Fortmann et al. (1991); Camann et al. 1993(a); Lewis et al. (1994); Simcox, (1995); Whitmore et al. 1994; Zahm et al. 1998), yet, there are no published data on pesticide dust levels in motor vehicles. Vehicles used to transport application personnel and equipment may be potentially contaminated with chemicals related to their work environment (Weisskopf et al. 1988). During trips into the occupational setting, motor vehicles used by agricultural workers have the potential to be contaminated by dust residues containing pesticides, metals, and PAHs. In-vehicle accumulation may subsequently lead to transfer of the residues to occupants (humans, pets, etc.) and into residential dwellings. A potentially large reservoir, dust embedded on the floors and upholstery of motor vehicles can become a long-term or chronic source of dermal and non-dietary oral exposure to the farm worker and his family. During the pilot phase of the Agricultural Health Study, Camann et al. 1993(a) concluded (after measuring child hand wipes and concentrations in indoor air, carpet dust and drinking water) that occupational exposures to the farmer were primarily responsible for the residential exposure of the farm family. Traditionally, in-vehicle human exposures to pollutants have focused primarily on air as the most important route of exposure. However, it has become increasingly apparent that exposure to chemical pollutants associated with dust may also be important (Camann, 1993; Lewis et al. 1994). Therefore, it is likely that routine placement of vehicles in agricultural fields could lead to subsequent contamination and continued accumulation of dust residues in this"microenvironment." In this pilot study, we will assess (for the first time) dust contaminant levels in motor vehicles used by agricultural workers. PURPOSE Pilot Study Objectives The main objective of this pilot study is to investigate the impact of dust residue levels for target classes of contaminants in motor vehicles on workers and their families in an agriculture-intensive region of California. A secondary objective is to perform an exposure assessment specific to the in-vehicle microenvironment for this sub-population. The study will measure levels of dust in motor vehicles from three classes of contaminants and evaluate whether certain populations (i.e. the agricultural community) are at greater risk due to high exposures. A third objective is to examine the temporal and spatial distributions of in-vehicle contamination. The study's sub-objectives are : To collect dust from farm worker vehicles To measure the levels of pesticide, metal and PAH residues in these vehicles To compare vehicles used in agricultural production with non-farm worker vehicles by comparing residue concentrations and surface loading To assess the sources of elevated dust levels, if possible. To incorporate the results into an aggregate risk calculation for the sub-population of farm workers. To determine if a more in-depth comprehensive assessment effort be under-taken to better characterize the problem. To develop an intervention program, as appropriate, if measured levels based on preliminary findings present a risk to occupants. To provide recommendations to reduce or mitigate exposure in this microenvironment. Expected Outcome. The output from this pilot study will provide data needed to better understand and expand exposure assessment methodologies to include the motor vehicle microenvironment and to provide inputs to better model children's exposure to environmental contaminants. TASKS DESCRIPTIONS The Contractor shall provide technical support to USEPA Region 9 by conducting quantitative and qualitative chemical analyses ofin-vehicle dust samples. In addition, the Contractor shall provide expertise and ongoing consultation throughout the Project. The Contractor shall prepare Statements of Work for analytic methods to be employed for the targeted analytes listed in attachments A-C. This may include identification of appropriate sampling procedures and protocols to be followed; required equipment/instrumentation, materials and supplies; and methods of sample acquisition, handling and specific analysis. Contractor shall submit full documentation for all modifications and/or non-standard methods to include quality control and Standard Operating Procedures (SOPs). Determination of quantitation limits for all modified methods shall be provided, as well as all method validation documentation on method detection limit; confidence and replicate precision data, and other associated validation (recovery, storage, and stability) studies. The Contractor shall provide all necessary sampling equipment required to ensure sample integrity. TheContractor shall possess (and may not subcontract) sufficient expertise to review and assure the quality control of all methods and protocols employed under this work assignment. The Contractor shall have sufficient expertise to provide technical support for data interpretation of environmental measurements and analytical results. The Contractor will be specifically chosen based on its knowledge and demonstrated experience in the following areas: Exposure assessment, evaluating how people are likely to come into contact with pollutants and quantifying the actual exposures thereof. Identification and measurement of emission sources and environmental concentrations in indoor dust. This would include a high degree of understanding of both chemical fate and transport and spatial/temporal variability. Demonstrated experience in dust analysis methodologies including the design, setup, and operation of complex sampling protocols. The Contractor shall provide data deliverables in an electronic format. DELIVERABLES AND PROJECT SCHEDULE Activity under this work assignment will be conducted for a twelve (12) month period beginning with the approval of the work plan. Deliverables shall include: Within sixty (60) days of receipt of statement of work, the Contractor shall submit a Draft Memorandum Summary of Methods. A meeting with the Project Manager shall be arranged within 2 weeks of submittal of this memorandum to discuss and finalize targeted analyte list. Within thirty (30) days of targeted analyte list finalization, a Draft Work Plan shall be submitted. (2 Copies to EPA.). Within thirty (30) days after Receipt of EPA=s comments, a final Work Plan shall be submitted. (3 copies.) Minimum of bi-weekly meetings with the Project Manager regarding project status and monitoring activities. Interim deliverable(s) in both electronic and paper copy of analytical data. CLP Level 4 data packages for all analyses. A final summary report of all analytical results. QUALITY ASSURANCE REQUIREMENTS The Contractor shall prepare a Work Plan and Quality Assurance Project Plan (which addresses project organization and the assignment of specific QA/QC activities) for the analyses of in-vehicle dust samples (EPA QA/G5, 1998). The implementation of the Work Plan will be in a phased, iterative approach designed to meet the overall study objective(s). BACKGROUND MATERIAL (contact Alvin Wong 415 744-1023 for attachments) Attachment A. Proposed Target Analyte List Pesticides (99) Attachment B. Proposed Target Analyte List PAHs (10) Attachment C. Proposed Target Analyte List Metals (33) Posted 08/12/99 (W-SN367013). (0224)

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