National Cancer Institute, Research Contracts Branch, PSAS, 6120 Executive Blvd, EPS/Room 638, Bethesda, MD 20892-7227

66 -- INSTRUMENTS & LABORATORY EQUIPMENT SOL RFQ-NCI-90171 DUE 090399 POC Cynthia Brown, Purchasing Agent, 301-402-4509, Todd Cole, Contracting Officer The National Cancer Institute (NCI), Laboratory of Cellular Carcinogenesis and Tumor Promotion intends to procure on a sole-source basis, an Automated Cellular Imaging System (ACIStm), from Chroma Vision Medical systems, Inc. the NCI investigator believes that the aforementioned instrument and organization is the only source that can satisfy their requirement. The imaging systems shall have the following features: shall include a high resolution microscope and high-powered camera coupled with automatic slide selection; shall can 10,000-20,000 nuclei within two(2) to ten (10), minutes, record the number of cells colored with the stain of interest, the number of cells not colored within the stain of interest and the average color of the colored cells; shall have automatic throughput walkaway capability (to process slides stacked in the instrument automatically while the instrument is unattended); shall include software to calculate the intensity of any color signal within cells on a slide; software shall allow semi-quantitative determination of five(5) different colors in the nucleus and simultaneously identify (without quantification) five(5) different colors in cytoplasm; shall have the ability to examine all the nuclei on a slide within two(2) to ten (10) minutes and store the coordinates of each area of interest and be retrievable on demand for future re-examination; shall have bright field photography to eliminate problems of color fading over time; shall produce a linear quantification for increases in nuclear color intensity; the system shall provide a large range of colors with high resolution (eg. Different tones of the same color shall be differentiated); shall be usable to determine a microdensitometry of polycyclic aromatic hydrocarbons (PAH) -- DNA adduct formation in human esophageal samples; the system shall include a microscope, tower and monitor, spare bulb, spray duster, blank slides, slide carriers, calibration slides, barcode labels, operators manual, installation, training, and one (1) year warranty; and, shall provide a Year 2000 Warranty for each hardware, software, and firmware product delivered. This is not a request for competitive quotation, however, if any interested party believes it can meet the above requirement, they may submit a statement of capabilities. Information furnished must be in writing and must contain sufficient detail, to allow NCI to determine if the party can meet the requirement. Capability statements must be received in the Contracts Office by 2:00 PM EST on September 03, 1999. If you have any questions, please contact Cynthia Brown, Purchasing Agent on (301) 402-4509. A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement. Posted 08/16/99 (W-SN368183). (0228)

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