National Cancer Institute, Research Contracts Branch, PSAS, 6120 Executive Blvd, EPS/Room 638, Bethesda, MD 20892-7227

66 -- MICROGENE CLIPPER SEQUENCER SOL RFQ90179-NS DUE 090799 POC Todd Cole, 301-402-4509 The National Institutes of Health (NIH), National Cancer Institute (NCI), Division of Clinical Sciences (DCS), Medicine Branch proposes to procure a MicroGene Clipper Sequencer from Visible Genetics, Inc., 700 Bay Street, Suite 1000, Toronto, Ontario, Canada MSG1Z6. The Medicine Branch currently has an Open Gene 2 Dye System that was purchased from Visible Genetics. The system is used in research to understand the mechanisms by which reconstitution of leukocytes occur after chemotherapy and/or bone marrow transplantation. The current system is utilized heavily by the Medicine Branch. The add on of a clipper sequencer will accommodate the increased usage by doubling the output capabilities of the current system in a seemless fashion. The system add-on shall have the following features: 1) The system shall be completely compatible with the existing Visible Genetics Open Gene 2 Dye System; 2) It shall have two dye, 16 lane automated DNA sequencing capability; 3) The instrument shall allow additional sequencing of 400 bases in 30 minutes (plus or minus five minutes); 4) It shall continue to enable the user to use Cy 5.5 and Cy 5 dye chemistries; 5) The instrument shall also include upgraded system software for the base system as well (GeneObjects Software v. 3.1 or equal). Since the MicroGene Clipper is an add-on system that is completely compatible to the existing Open Gene 2 Dye System, Visible Genetics is the only source know by the NCI researcher that can meet the above requirement. This is not a request for competitive quotation. However, if any party believes it can meet the above requirement, it may submit a statement of capabilities. The statement of capabilities and any other information furnished must be in writing and must contain material in sufficient detail to allow NCI to determine if the party can perform this requirement. Capability statements must be received in the contracting office by 3:00 p.m. EST, on September 7, 1999. If you have any questions, please contact Marsha Gorham, Purchasing Agent on (301) 402-4509. A determination by the Government not to compete this proposed requirement based upon responses to this notice is solely within the discretion of the Government. Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement. Posted 08/19/99 (W-SN370064). (0231)

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