National Cancer Institute, Research Contracts Branch, PSAS, 6120 Executive Blvd, EPS/Room 638, Bethesda, MD 20892-7227

B -- COLLECTION OF TISSUE & BLOOD SAMPLES SOL RFQ-NCI-90183-NR DUE 090799 POC Marsha Gorham, Purchasing Agent & Todd Cole, Contracting Officer The National Cancer Institute(NCI), Division of Cancer Epidemiology and Genetics (DCEG), Environmental Epidemiology Branch (EEB) plans to procure the services of the Department of Urology, University of California at San Francisco (UCSF), 400 Parnassus Avenue, A610, San Francisco, CA 94143 to collect tissue samples from Asian Americans and patients undergoing cystoprostatectomy. NCI is conducting a methodologic study to correlate tissue levels of hormones with serum levels in order to clarify whether circulating levels of hormones reflect hormonal status in the prostate gland. In addition, racial variation in the correlations will be evaluated by the National Cancer Institute. The purpose of this requirement is for the collection of prostatic tissue and blood. Of special interest is the collection of tissue samples from Asian Americans and from patients undergoing cystoprostatectomy. A total of 100 men undergoing prostatectomies shall be recruited into the study for tissue and fasting blood collection. Two 20-mg pieces of frozen tissue should be collected from each of the three sites in the prostate gland, including the transitional, central,and peripheral zones. In total, 6 pieces of tissue and 30ml of fasting blood shall be collected from each of the 100 study subjects for a total of 600 tissue samples and 100, 30 ml blood samples. The above collection must be completed within twelve months in order for NCI to maintain the overarching study's schedule. The University of California at San Francisco can readily perform the specimen collection services noted above. The University of California at San Francisco has a sufficient number of Asian-Americans available to participate in the study. In addition, the clinical center at the University has extensive experience and expertise in cystoprstatectomy, a complex and relatively rare procedure. UCSF is the only source known to the NCI Research that has this combination of expertise in procedures and a significant Asian-American population. This is not a request for competitive quotation. However, if any interested party believes it can perform the above requirement, it may submit a statement of capabilities. The statement of capabilities and any other information furnished must be in writing and must contain material in sufficient detail to allow NCI to determine if the party can perform this requirement. Capability statements must be received in the contracting office by 3:00 p.m. EST, on September 7, 1998. If you have any questions, please contact Marsha Gorham, Purchasing Agent on (301) 402-4509. A determination by the Government not to compete this proposed requirement based upon responses to this notice is solely within the discretion of the Government. Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement. Posted 08/20/99 (W-SN370624). (0232)

Loren Data Corp. http://www.ld.com (SYN# 0009 19990824\B-0001.SOL)