National Institutes of Health, National Institute of Allergy and Infectious Diseases, Contract Management Branch, Room 2230, 6700-B Rockledge Drive, MSC 7612, Bethesda, MD 20892-7612

A -- CONFIRMATORY IN VITRO VIROLOGICAL EVALUATIONS FOR HIV/AIDS SOL RFP NIH-NIAID-DAIDS-00-30 DUE 112699 POC Dee Dee Moss, Contract Specialist, (301) 402-5825 The National Institute of Allergy and Infectious Diseases (NIAID), NIH, has a requirement to identify and develop novel therapeutic approaches for the prevention and treatment of human immunodeficiency virus (HIV) infections. Many investigators and drug sponsors who have identified a lead compound lack the capability and capacity to assess further their compound through in vitro confirmatory antiviral testing in additional test systems or in combination with other agents for the treatment of acquired immunodeficiency syndrome (AIDS) and associated opportunistic infections (OIs). This type of informa-tion is needed by drug sponsors and the Government to formulate and prioritize developmental plans for potential new therapies. A contract is planned to perform in vitro confirmatory testing of therapies for anti-HIV activity and in vitro evaluation of antiretroviral agents in combination with other AIDS therapies. It is anticipated that one (1) cost reimbursement, completion type contract will be awarded for a period of seven (7) years, beginning approximately September 1, 2000. RFP NIH-NIAID-DAIDS-00-30 will be available electronically on or about September 3, 1999, and may be accessed through the NIAID Contract Management Branch (CMB) Home Page by using the following electronic address and instructions: NIAID/CMB Home Page (via the WWW): Use http://www.niaid.nih.gov/contract to access the NIAID/CMB Home Page. Once at the NIAID/CMB Home Page, click on the "RFPs" link and then click on "RFP NIH-NIAID-DAIDS-00-30." Please note that the RFP for this acquisition has been revised to include only the Work Statement, Deliverable and Reporting Requirements, Special Requirements and Mandatory Qualification, if any, the Technical Evaluation Criteria, and the Specific RFP Instructions and Provisions. All information required for the submission of an offer will be contained in the electronic RFP package. Following proposal submission and the initial review process, Offerors comprising the competitive range may be requested to provide additional documentation to the Contracting Officer. Responses to this RFP will be due on or about November 26, 1999. Any responsible Offeror may submit a proposal, which will be considered by the Government. This advertisement does not commit the Government to award a contract. Point of Contact: Dee Dee Moss, Contract Specialist. Electronic mail address: dg25a@nih.gov Telephone: (301) 402-5825 FAX: (301) 480-5253 No collect calls will be accepted. Posted 08/24/99 (W-SN371630). (0236)

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