National Cancer Institute, Research Contracts Branch, PSAS, 6120 Executive Blvd, EPS/Room 638, Bethesda, MD 20892-7227

66 -- INSTRUMENTS & LABORAROTY EQUIPMENT SOL RFQ-NCI-90230 DUE 092399 POC Cynthia Brown, Purchasing Agent, 301-402-4509, Todd Cole, Contracting Officer The National Cancer Institute (NCI), Division of Clinical Sciences (DCS), Medicine Branch (MB) plans on procuring a colonoscope with high resolution digital signal video processor with an integrated data system from Fujinon, Inc., 10 Highpoint Drive, Wayne, New Jersey 07470. The Fluorescence In-Situ Hybridization (FISH) section of the Medicine Branch focuses on the delineation of chromosomal aberrations involved in the -e origin of human genetic diseases using modern cytogenetic methods. Research is particularly aimed at the identification of genetic events during initiation and progression of solid tumors using comparative genomic hybridization, interphase cytogenetics, digital image analysis, and confocal laser scanning microscopy.A current study involves the examination and biopsy of tissue from cancer patients during colonoscopy procedures. Careful examination and visualization of the tissue is critical to a safe and effective procedure for both the researcher and patient. In performing the currentstudy, a shorter procedure is also desirable for the safety of the patient since less medication is required. As a result, the required colonoscope shall have a high resolution digital signal video processor with an integrated data system, and it shall be self-contained with magnifying zoom. The colonoscope shall provide at least 410,000 pixels or higher resolution and very clear freeze frame images. The instrument shall have an observation range of 5 to 20 mm. or greater magnification. Higher resolution and magnification are essential elements for the work to be performed since less time to focus and clearly visualize the tissue is needed. Fujinon is the only source known to the NCI Researcher that can meet the above requirements, especially with regard to the required resolution and magnification This is not a request for competitive quotation. However, if any interested party believes it can meet the above requirement, it may submit a statement of capabilities. The statement of capabilities and any otherinformation furnished must be in writing and must contain material in sufficient detail to allow NCI to determine if the party can meet the above requirements. Capability statements must be received in the contracting office by 3:00 p.m. EST, on September 23, 1999. If you have any questions, please contact Cynthia Brown, Purchasing Agent on (301) 402-4509. A determination by the Government not to compete this proposed requirement based upon responses to this notice is solely within the discretion of the Government. Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement. Posted 09/03/99 (W-SN376148). (0246)

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